摘要
对非Ｏ１群霍乱弧菌进行准确分型和分类，是目前亟待解决的重要问题。应用多位点酶电泳地对来源不同的９８株非Ｏ１群乱弧菌进行１２个酶基因位点的检测和分子分型研究。结果：９８例非Ｏ１群霍乱弧菌可以分为５９个ＥＴ型，每个型别所包含的菌株数较少。
Vibrio cholerae can be classified into more than 155 serogroups by the serotyping method. Vibrio cholerae O1 and O139 are recognized the pathogens of epidemic cholera. Others are considered to be general diarrhoeal pathogens or the environmental bacteria. In order to type non O1 strains more powerfully, 98 strains of non O1 were studied with MEE,and 59 ETs were obtained depending on the detection of 12 enzymes. By the cluster analysis , 59 ETs were classified into 22 clonal clusters (CL) which were geographical, e.g. CL E included most of the strains isolated from Xinjiang during the year 1990 to 1991, CL N included most of the strains isolated from Hebei during the year 1988 to 1989. Compared with those of VC O1, especially with epidemigenic strains, the relationships between different ETs of non O1 strains were disperse.
作者
段广才
高守一
Duan Guangcai 1) , Gao Shouyi 2) , Liu Yanqing 2) , Qi Guoming 2) , Zhang Lijuan 2) 1)Department of Epidemiology, College of Public Health, Henan Medical University, Zhengzhou 450052 2)Institute of Epidemiology and Microbiology, C
出处
《河南医科大学学报》
1998年第3期 18-23,共6页
Journal of Henan Medical University
关键词
非O1群
霍乱弧菌
多位点酶电泳
分型
数值分类
Vibrio cholerae non O1
multilocus enzyme electrophoresis
typing
numerical taxonomy
