摘要
目的利用响应曲面法研究从紫茎泽兰中提取黄酮的最佳工艺条件。方法使用单因素实验方法考察乙醇浓度,提取温度,料液比以及提取时间对黄酮得率的影响,使用响应曲面法优化提取工艺。结果最优的工艺条件为:固液比为1∶30(g∶ml),提取时间为2.6 h,乙醇浓度为50%,提取温度为64℃。结论使用响应曲面法能合理的优化紫茎泽兰中黄酮的提取工艺,为紫茎泽兰的综合利用提供参考。
Objective To optimize the extraction condition for Eupatorium adenophorum Spreng by response surface methodology. Methods We adopted the single -factor experimental method to study the influence of mass concentration of ethanol, extraction temperature, solid -liquid ratio and extraction time, and used the response surface methodology to optimize the extraction technique. Results The optimal condition was as follows ： the solid to liquid ratio was 1 ： 30 （g/ml） , the extraction time was 2.6 hour, the mass contraction of ethanol was 50% and the extraction temperature was 64 degree. Conclusion The experimental method can optimize the technique well and it also provide an appropriate way to synthetically utilize eupatorium adenophorum spreng.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2009年第9期2331-2333,共3页
Lishizhen Medicine and Materia Medica Research
关键词
紫茎泽兰
黄酮
响应曲面法
Eupatorium adenophorum Spreng
Flavonoids
Response surface methodology
