摘要
目的回顾性分析总结影响子宫内膜癌复发的高危因素。方法对2000年12月至2004年12月收治的189例子宫内膜癌病例进行回顾性分析,进一步探讨病理类型、组织学分级、肌层浸润深度、淋巴结转移、手术病理分期、合并症与复发之间的关系。结果手术病理分期,不同病理类型、组织学分级,有无肌层浸润和淋巴结转移中患者的缓解曲线比较,结果均P<0.05,差异有统计学意义;有无合并糖尿病、高血压或肥胖患者的缓解曲线比较,结果均P>0.05,差异无统计学意义。COX回归多因素分析,肌层浸润深度及术后病理类型对复发的影响有统计学差异,P<0.05。结论特殊病理类型、组织学低分化、深肌层浸润、淋巴结转移、期别晚是复发的高危因素。
Objective To analyze high risk factors for prognosis of endometrial carcinoma. Methods To summarize the influence of pathologic type, histologic grade, myometrial invasion depth, lymph node metastasis, surgical-pathologic stage and complications on prognosis of 189 cases with endometrial carcinoma from Dec. 2000 to Dec. 2004. Results The comparisons of the alleviate curves in different surgical-pathologic stages, pathologic types , histologic grades, different depth of myometrial invasion , and wether with lymph nodemetastasis were both P 〈 0. 05, they indicated the differences were statistically significant. The comparisons of the alleviate curves in wether with diabetes, hypertension or fat were both P 〉 0. 05, they were not statistically different. By multivariate analysis, depth of myometrial invasion and special pathologic type were independent high risk factors for the recurrence （P 〈 0. 05）. Conclusion Special pathologic types, high histological grade, deep myometrial invasion, lymph node metastasis, late-stages are high risk factors of recurrence.
出处
《中国实用医药》
2009年第25期1-3,共3页
China Practical Medicine
基金
国家自然科学基金(项目编号:30772332)
广东省自然科学基金(项目编号:7001568)
广东省科技计划项目(项目编号:2007B030502014)
广州市科技计划项目(项目编号:2007Z3-E0601)
关键词
子宫内膜癌
高危因素
复发
Endometrial carcinoma
High risk factor
Recurrence
