摘要
目的:比较不同胰岛素给药方法对糖尿病酮症酸中毒(DKA)的治疗差异。方法:60例糖尿病酮症酸中毒患者随机分为胰岛素泵皮下输注组(CSII组,30例)和常规小剂量胰岛素静脉滴注组(IVI组,30例),观察2组患者血糖(空腹及餐后2 h血糖)的变化、尿酮体转阴时间、平均胰岛素用量及低血糖发生率的差异。结果:CSII组血糖达标时间、尿酮体转阴时间较IVI组明显缩短(P<0.01);平均胰岛素用量少于IVI组(P<0.05)。低血糖发生率明显低于IVI组(P<0.01)。治疗前、后空腹及餐后2 h血糖水平两组间差异无统计学意义(P>0.05)。结论:胰岛素泵治疗较常规小剂量胰岛素静脉滴注短期疗效更安全、有效。
Objective: To compare the effect of insulin pump (continues subcutaneous insulin injection,CSII) and insulin venous instilling (IVI) in treatment of diabetic ketoaeidosis(DKA). Methods: Patients with DKA (n :60) were chosen for comparing the effect between intravenous insulin instilling treatment and CSII therapy. Results: Both CSII and insulin instilling controlled DKA effectively, but the former surpassed the latter in the therapeutic respects of insulin dosage,hypoglycemic speed,glycemic stability,ketobody clearance. Conclusion: CSII has an advantage over insulin instilling in treatment of DKA.
出处
《新疆医科大学学报》
CAS
2009年第8期1083-1084,共2页
Journal of Xinjiang Medical University