摘要
目的:观察双参胶囊降血糖作用.方法:采用四氧嘧啶造模和葡萄糖氧化酶法测血糖.结果:①对正常小鼠血糖无影响(P>0.05);②0.40,0.80gkg-1剂量组对四氧嘧啶糖尿病小鼠的血糖具有明显降低作用(P<0.01);③ip和ig给药对模型动物血糖均有显著影响(P<0.01);④0.40gkg-1双参胶囊ig6d开始明显降低模型动物血糖(P<0.01).结论:0.
Aim:To explore the function of Shuangsen Capsule on reducing the plasma glucose of mice. Methods: Hyperglycemia mice models were prepared by iv alloxan and the index of plasma glucose was measured by glucousoxidase method. Results: ①Shuangsen Capsule had no effect on normal mice' plasma glucose ( P >0.05); ②Two dosages of 0.40 g·kg -1 and 0.80 g·kg -1 also reduced the hyperglycemia mice' plasma glucose ( P <0.01); ③Given ways of ig and ip did the same function on reducing hyperglycemia mice' plasma glucose ( P <0.01); ④After 6 d, the function of ig Shuangsen Capsule by 0.40 g·kg -1 per day, on reducing hyperglycemia mice' plasma glucose was observed ( P <0.01). Conclusion: Ig Shuangsen Capsule by 0.40 g·kg -1 per day, the function of reducing hyperglycemia mice' plasma glucose was significant.
出处
《第四军医大学学报》
1998年第3期277-278,共2页
Journal of the Fourth Military Medical University