摘要
目的评价甲冰缓释膜在宫颈环形电切术后的临床疗效。方法将行宫颈环形电切术的240例患者随机分为2组,各120例。治疗组手术部位使用甲冰缓释膜,对照组口服甲硝唑片0.2 g,tid,疗程均为7 d。观察阴道出血排液及持续时间、宫颈出血率、手术创面愈合时间等指标,比较治疗效果。结果①治疗组阴道出血、排液及持续时间均少于对照组(P<0.05),术后宫颈出血发生率显著低于对照组(P<0.01);②创面愈合时间较对照组缩短,4周内愈合率明显升高(P<0.05)。结论甲冰缓释膜可促进宫颈创面愈合,减少创面感染、渗出、出血,减少宫颈环形电切术后并发症。
Objective To investigate the clinical effect of the slow-release films of metronidazole and borneol after loop electrosurgical excision procedure(LEEP). Methods 240 patients with cervical intraepithelial neoplasia underwent LEEP were taken for study, and were divieded into two groups randomly : the treatment group, which used metronidazole-borneol sustained-release films, while the control group was orally given with metronidazole tablets. All the patients were followed up, and observed the vaginal bleeding and duration, the rate of cervical bleeding, healing time of surgical wound. Results (1) The vaginal bleeding, liquid discharge and duration time in the treatment group were significantly less than those in the control group (P 〈0.05), cervical bleeding after the proportion was significantly lower than the control group(P 〈 0.01 ). (2)The wound healing time in the treatment group was shorter than that in the control, especially healing rate within four weeks was significantly higher (P 〈 0.05). Conclusion The metronidazole-borneol sustained-release films could improve the restoration of cervical wound after LEEP, reduce wound infection, leakage, bleeding, and postoperative complications.
出处
《医药导报》
CAS
2009年第9期1142-1144,共3页
Herald of Medicine
关键词
甲冰缓释膜
宫颈环形电切术
Metronidazole-borneol sustained-release films
Loop electrosurgical excision procedure