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静脉注射免疫球蛋白治疗多发性硬化急性期疗效观察 被引量:3

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摘要 目的探讨静脉注射大剂量免疫球蛋白(IVIG)治疗缓解复发型多发性硬化(MS)急性复发的疗效。方法选择2003年2月至2007年4月住院的缓解复发型MS病例中第1次复发的病例58例,其中用IVIG治疗组28例,选同期未用IVIG治疗病例30例作为对照,两组其他治疗均相同。观察两组治疗前后的残疾状态扩展评分(EDSS)及再次复发情况。结果 IVIG治疗组的治疗后15天及21天的EDSS评分均明显优于对照组,且治疗后2年内的再次复发率明显低于对照组。结论静脉注射大剂量免疫球蛋白对于缓解复发型MS急性复发的患者有确切疗效,且能降低再次复发几率。
出处 《中国医刊》 CAS 2009年第9期40-41,共2页 Chinese Journal of Medicine
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  • 1秦超,莫雪安,赖永榕,凌莉,孙圣刚,童萼塘.自体外周血干细胞移植治疗重症肌无力的并发症及其防治(附3例报告)[J].广西医科大学学报,2004,21(2):249-250. 被引量:7
  • 2李亚红,王黎明,田丁军,张艳,陈锟,王晓燕,吕文红.自体干细胞移植治疗重症肌无力一例报告[J].中华神经科杂志,2005,38(4):219-219. 被引量:7
  • 3Fassas A,Anagnostopoulos A,Kazis A,et al.Peripheral blood stem cell transplantation in the treatment of progressive multiple sclerosis:first results of a pilot study[J].Bone Marrow Transplant,1997,20:631-638. 被引量:1
  • 4Burt RK,Traynor AE,Cohen B,et al.T cell-depleted autologous hematopoietic stem cell transplantation for multiple sclerosis:report on the first three patients[J].Bone Marrow Transplant,1998,21:537-541. 被引量:1
  • 5Carreras E,Saiz A,Marin P,et al.CD34+ selected autologous peripheral blood stem cell transplantation for multiple sclerosis[J].Haematologica,2003,88 (3):306-314. 被引量:1
  • 6Salzman D,Tami J,Jackson C,et al.Clincial remission of myasthenia gravis in a patient after high dose therapy and autologus transplantation with CD34+ stem cell[J].Blood,1994,84 (supp l):206a. 被引量:1
  • 7Euler HH,Marnont AM,Bacigalupo A,et al.Early recurrence or persistence of autoimmune diseases after unmanipulated autologous stem cell transplantation[J].Blood,1996,88:3621-3625. 被引量:1
  • 8Schulenburg A,Haas M,Goldammer A,et al.Autologous stem cell transplantation for refractory myasthenia gravis[J].Bone Marrow Transplantation,2002,29:472a. 被引量:1
  • 9Yoshinobu Iwasaki,Shuji Ohsugi,Yoshizumi Takemura,et al.Multidisciplinary therapy including high2dose chemotherapy followed by peripheral blood stem cell transplantation for invasive thymoma[J].Chest,2002,122:2249-2252. 被引量:1
  • 10陆道培,黄晓军.骨髓移植.见:邓家栋,杨崇礼,等.临床血液学[M].上海:上海科学技术出版社,2001.1677-1678. 被引量:1

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同被引文献26

  • 1肖桂荣,邵静松,孙新芳,宋建良.多发性硬化认知功能障碍的特点[J].中华老年医学杂志,2007,26(6):429-431. 被引量:1
  • 2Polman CH,Reingold SC,Edan G,et al.Diagnostic criteria for multiple sclerosis:2005 revisions to the "McDonald Criteria"[J].Ann Neurol,2005,58:840-846. 被引量:1
  • 3Polman CH,Reingold SC,Banwell B,et al.Diagnostic Criteria for Multiple Sclerosis:2010 Revisions to the McDonald Criteria[J].Ann Neuro,2011,69:292-302. 被引量:1
  • 4Bergendal G, Martola J, Stawiarz L. Callosal atrophy in multiple scle- rosis is related to cognitive speed [ J ]. Acta Neurologica Scandinavi- ca,2013, 127(4) :281-289. 被引量:1
  • 5Till C, Racine N, Araujo D. Changes in Cognitive Performance Over a 1-Year Period in Children and Adolescents With Multiple Sclerosis[J]. Neuropsychology,2013, 27(2) :210-219. 被引量:1
  • 6Tur C, Ciccarelli O. An overview of the association between gray matter damage and cognitive impairment in multiple sclerosis [J] Neurodegenerative Disease Management,2012, 2(5) :503-515. 被引量:1
  • 7Bodling AM, Denney D, Lynch SG.. Individual Variability in Speed of Information Processing: An Index of Cognitive Impairment in Mul- tiple Sclerosis[J]. Neuropsychology,2012,26(3) :357-367. 被引量:1
  • 8Bermel RA, Weinstock-Guttman B, Bourdette D, et al. Intra- muscular interferon beta-la therapy in patients With relap- sing-remitting multiple sclerosis:a 15-year follow- up study [J]. Muh Scler,2010,16(5) :588 "596. 被引量:1
  • 9Elovaara I, Kuusisto H, Wu X,'et al. Intravenous inununo- globulins are a therapeutic option in the treatment of multi- ple sclerosis relapse. Clin Neuropharmacol, 2011,34 ( 2 ) : 84 - 89. 被引量:1
  • 10刘恋,黄红娥,刘忆.磁共振常规和弥散加权成像技术对多发性硬化的诊断价值[J].中国临床医生杂志,2008,36(2):35-36. 被引量:8

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