摘要
目的探讨失血性休克对重度颅脑损伤并发应激性溃疡的影响。方法428例重度颅脑损伤患者根据有无合并失血性休克分为两组（休克组133例、无休克组295例），观察两组发生应激性溃疡、胃液和血液的pH值等情况。结果428例重度颅脑损伤患者并发应激性溃疡112例（26．2％），其中休克组75例，占失血性休克的56．4％（75／133），无休克组37例，占无失血性休克的12．5％（37／295），两组比较差异有统计学意义（x^2=91．23，P〈0．01）；伤后第2天两组患者血液中的pH值分别为：7．24±0．11和7．32±0．17，两组比较差异有统计学意义（t=5．797，P〈0．01），第7天两组血液中的pH值分别为：（7．34±0．11）和（7．33±0．15），两组比较差异无统计学意义（t=0．769，P〉0．05）；伤后第2天两组患者胃液中的pH值分别为：（2．88±0．29）和（2．84±0．35），第7天胃液中的pH值分别为：（3．21±1．44）和（3．45±1．05），两组比较均无统计学意义（t=1．231、1．714，P〉0．05）。结论失血性休克在重型颅脑损伤并发应激性溃疡中起重要作用。
Objective To study the role of hemorrhagic shock in severe craniocerebral trauma with stress ulcer. Methods The clinical data of 428 patients of severe craniocerebral trauma in our hospital from January 2001 to January 2009 were divided into two groups according to whether or not merging with hemorrhagic shock. The incidence of stress ulcer in two groups was calculated and the PH of gastric juice and blood in different periods were measured. Results Stress ulcer developed in 56.4% （75/133） of patients with hemorrhagic shock and 12.5 % （37/295） of patients with hemorrhagic shock-free,with significant difference between the two groups（ P 〈 0. 01 ）. Blood pH differed significantly（P 〈 0. 01 ） on 2d, but not on 7d （ P 〉 0. 05 ） after injury between the two groups. There was no significant difference in gastric juice pH on 2d and 7d after injury between the two groups（P 〉0. 05）. Conclusion Hemorrhagic shock plays an important role in severe craniocerebral trauma with stress ulcer.
出处
《中国基层医药》
CAS
2009年第8期1416-1417,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
休克
失血性
颅脑损伤
溃疡
Shock, Hemorrhagic
Craniocerebral trauma
Ulcer
