摘要
目的观察急性脑梗死患者血浆D-二聚体水平的变化及临床意义。方法对71例急性脑梗死患者急性期、恢复期和64例健康体检者采用双抗体夹心法检测血浆D-二聚体水平。结果急性脑梗死患者急性期血浆D-二聚体水平：72h（1．54±0．91）mg/L、第7天（1．32±0．86）mg/L，较恢复期第15天（0．49±0．31）mg／L、第30天（0．32±0．14）mg／L和健康体检者（0．31±0．81）mg/L明显增高（t=2．576、t=2．807，P〈0．01）。结论检测血浆D-二聚体可作为急性期脑梗死病情判定及疗效观察的有效指标。
Objective To throagh observing the change of plasma D-Dimer level in the acute cerebral infarction patients to provide the experimental foundation for further research of pathology, physiology pathological process judgment and observation of curative effect. Methods To measure the plasma D-Dirner level by ELISA in 71 cases of acute wrebral infarction patients and 64 healthy controls. Results The plasma D-Dimer level in the acute cerebral infaretion patients in acute period was 72h （ 1.54 ± 0. 91 ） mg/L,7d （ 1.32 ±0. 86） mg/L significantly higher than 15d （ 0. 49 ± 0. 31 ） mg/L,30d （ 0. 32 ±0. 14） mg/L at resume period patients and （ 0. 31± 0. 81 ） mg/L at normal controls and dropped in resume period（ t = 2. 576,t = 2. 807 ,P 〈 0. 01 ）. They had significant difference. Conclusion The resuhs indicate that acute cerebral infarction is in the manifestation of hyper coagulation, plasma D-Dimer measuring was valuable for pathological process judgment and observation of curative effect of acute cerebral infarction.
出处
《中国基层医药》
CAS
2009年第8期1412-1413,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
脑梗死
纤维白降解物
Brain infarction
Fibrin degradation prodacts
