摘要
目的探讨宫腔镜下输卵管通液中加入激素治疗输卵管阻塞性不孕症的疗效。方法将该院2005年1月～2007年6月诊治的输卵管阻塞性不孕症患者104例随机分为两组,利用宫腔镜直视下输卵管插管加压疏通。对照组通液为生理盐水20mL,激素组通液为生理盐水20mL加地塞米松5mg。每月注射1次,连续3个月。随访2年,评价输卵管通畅情况、受孕情况、并发症产生情况。结果通液治疗后4个月,激素组通畅有效率为88.5%;对照组为74.1%。激素组优于对照组(χ2=7.450,P=0.024)。随访2年内,激素组受孕59.6%,对照组受孕38.5%。激素组优于对照组(χ2=4.656,P=0.031)。其OR值为2.362,95%CI为1.002～5.599。而两组并发症产生情况相当(χ2=0.088,P=0.767)。结论宫腔镜通液术治疗输卵管阻塞引起的不孕症时,在通液中加入地塞米松,可提高疗效。
[ Objective ] To investigate the value of hormone therapy in hydrotubation with hysteroscope for tubal obstruction infertility treatment. [Methods] From January 2005 to June 2007, 104 cases of infertility with tubal obstruction were randomly divided into two groups. In the control group, hydrotubation was done with 20 mL of normal saline solution. In the hormone group, 20 mL normal saline and 5 mg dexamethasone were used for hydrotubation. Each patient received 1 injection per month for 3 successive months. In the follow-up of 2 years, tubal patcney, the rate of pregnancy, the complications were evaluated. [ Results ] In the 4th month after treatment, the patency rate was 88.5% in the hormone group and 74.1% in the control group （χ^2 =7.450, P =0.024）. The pregnancy rate was 59.6% in the hormone group and 38.5% in the control group （χ^2= 4.656, P =0.031）.The OR was 2.362, 95%, CI was 1.002-5.599. The two groups had the same chance of complications （χ^2=0.088, P =0.767）. [ Conclusion ] Dexamethasone may enhance the effectiveness of hydrotubation with hysteroscopy for the treatment of infertility caused by fallopian tube obstruction.
出处
《中国内镜杂志》
CSCD
北大核心
2009年第8期801-803,共3页
China Journal of Endoscopy
