摘要
目的观察舒芬太尼预防腭咽成形术患者术后苏醒期躁动的效果。方法将90例ASA1～2级择期行腭咽成形术的患者随机分为A、B、C3组，每组30例。3组均用咪唑安定＋芬太尼＋丙泊酚＋阿曲库铵诱导，术中以丙泊酚＋瑞芬太尼维持麻醉。在术毕前停麻醉时A组静脉注射生理盐水4mL，B组静脉注射氯诺昔康0．2mg／kg，C组静脉注射舒芬太尼0．06μg／kg，分别记录麻醉前患者的呼吸次数、麻醉时间、自主呼吸恢复时间、拔管时间、拔管时镇静-躁动评分（RASS）及拔管后5min、10min的呼吸次数、全麻后身体舒适度评分（BCS）和副作用。结果C组拔管后5min呼吸次数低于A组和B组（P〈0．05）；3组RASS评分及BCS评分比较有统计学意义（P〈0．05）；B、C组的副作用主要是恶心。结论舒芬太尼能有效抑制腭咽成形术患者术后苏醒期躁动的发生，且副作用少。
Objective To explore the effect of sufentanil on restlessness in the awake period of patients with uvulopalatopharyngoplasty（UPPP）. Methods 90 cases of UPPP were randomly divided into three groups with 30 cases in each group, and each group was induced with midazolam, propofol and atracurium , and then, propofol and remifentanil were used to maintain anaesthesia. When the anaesthesia was stopped just before the completion of the operation, Group A was given intraveneous injection of 4 mL of saline solution, Group was given intraveneous injection of 0.2 mg/kg of lomoxicam, and Group C was given intraveneous injection of 0.06 μg/kg of sufentanil. The times and the period of breath before anaesthesia, the time of the restoration of spontaneous breathing, the time of extubation, the RASS scores when the extubation was done 5 minutes later and 10 minutes later, the physical comfort after general anaesthesia and the side effects were recorded respectively. Results The times of breathing were less in Group C than in Group A and Group B（ P 〈 0.05）. There existed significant difference in RASS scores and BCS scores between the three groups（ P 〈0.05）. The main side effect in Group B and Group C was Nausea. Conclusion Sufentanil can effectively prohibit the restlessness in the awake period of patients with UPPP.
出处
《山东医学高等专科学校学报》
2009年第5期383-385,共3页
Journal of Shandong Medical College
关键词
舒芬太尼
腭咽成形术
苏醒期躁动
Sufentanil
Uvulopalatopharyngoplasty
Restlessness in awake period
