摘要
目的探讨液基薄层细胞制片技术在肺肿瘤诊断中的应用价值。方法选取纤维支气管镜刷检细胞学诊断1580例肺肿瘤患者,同时采用常规刷片、液基薄层细胞制片进行细胞学诊断,并随诊患者的临床及病理资料。结果1580例标本中经组织病理诊断肺部恶性肿瘤864例,常规刷片诊断747例,液基薄层细胞制片诊断795例,液基薄层细胞学、常规刷片诊断敏感度分别为92%、86%,特异性分别为95.1%、84%。液基薄层细胞学、常规刷片分型诊断符合率分别为:鳞癌96.2%、93.5%,腺癌94.3%、87%,小细胞癌98%、90%。结论纤维支气管镜液基薄层细胞技术在肺肿瘤诊断中具有较高的特异性及分型诊断符合率。
Objective To evaluate the ThinPrep cytology test in the diagnosis of lung cancers. Methods Thinprep bronchial brushing cytology test and conventional preparation examination were applied to the diagnosis of a total of 1 580 selected patients. Data from the patients were collected, and the related clinical and pathological data were analyzed. Results A total of 864 malignant patients were confirmed with histopathological diagnosis, 747 malignant patients confirmed with conventional preparation diagnosis, and 795 with Thinprep cytology test. For Thinprep cytology test and conventional preparation diagnosis, the sensitivity were 92% and 86% respectively, and the specificity were 95. 1% and 84% respectively. The subclassification accordant rate of the two methods were 96.2% and 93.5% respectively in squamous cell carcinoma, 94.30/6o and 87% respectively in adenocarcinoma, and 98% and 90%respectively in small cell lung cancer. Conclusion ThinPrep bronchial brushing cytology has good sensitivity and specificity in the typing and diagnosis of lung cancer.
出处
《现代药物与临床》
CAS
2009年第4期244-246,共3页
Drugs & Clinic
