摘要
目的探讨放射治疗与微波热疗联合治疗晚期颈部淋巴结转移癌的临床疗效。方法对60例颈部淋巴结转移癌患者行单纯放疗和放疗加微波热疗,单纯放疗组:采用直线加速器6MV-X治疗,累计肿瘤剂量60～70 Gy/6～7周;放疗加微波热疗组:放疗同单纯放疗组,微波热疗采用HG-2000型微波治疗机对颈部淋巴结转移灶区域局部体外加热。30～40 min/次,2次/周,治疗结束后3月进行疗效评价。结果单纯放疗组CR 30.0%,放疗加微波组CR 56.7%,两者之间比较有显著性差异(P<0.05);总有效率(CR+PR)单纯放疗组63.3%,放疗加热疗组CR+PR 90.0%,两者之间有显著性差异(P<0.05)。结论微波热疗对放疗有协同增敏作用,二者配合对颈部较淋巴结转移癌的治疗有重要的临床应用价值。
Objective To explore the clinical efficacy of metastatic carcinoma of cervical node with radiation therapy and microwave therapy. Methods Sixty patients with metastatic cervical node were treated with radiation therapy alone and radiation therapy with microwave therapy. Radiation therapy group alone ： liner accelerator 6MV - X was used to give 60 -70 Gy in 6 to 7 weeks;Radiation therapy and microwave therapy group： HG -2000 microwave machine was used to treat metastatic cervical node for 2 times in one week ,30 or 40 minutes per time. The clinical efficacy was evaluated 3 months later. Results Complete response rates were 30.0% and 56.7% in radiation therapy group alone and radiation therapy with microwave therapy group, respectively. There was obvious difference in response between the two groups （ P 〈 0. 05 ） ; the total effective rate were 63.3% and 90.0% in two groups, including complete responses and partial responses . There was obvious difference in response between the two groups （ P 〈 0.05 ）. Conclusions The combination of two methods is effective and significantly superior to single treatment of radiotherapy.
出处
《医学信息（内.外科版）》
2009年第7期601-602,共2页
Medical Information Operations Sciences Fascicule
关键词
颈部淋巴结转移癌
放射治疗
微波治疗
cervical lymph node metastatic carcinoma
radiation
microwave therapy
