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半边莲化学成分的研究 被引量:10

Chemical constituents of Lobelia chinensis
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摘要 目的:研究半边莲Lobelia chinensis Lour.全草的化学成分。方法:用溶剂提取、萃取、硅胶正相柱色谱及结晶法进行化学成分的分离纯化,通过理化性质和波谱分析鉴定结构。结果:从半边莲全草中分离鉴定了7个化合物,结构分别为:5-羟基-4′ -甲氧基黄酮-7-O-芸香糖苷(1),正丁基-O-β-D-吡喃果糖苷(2),5,7-二甲氧基香豆精(3),cirsiumaldehyde(4),香叶木素(5),5-hydroxymethyl-2-furancarboxaldehyde(6)和6-羟基-7-甲氧基香豆精(7)。结论:化合物2~4,6,7为首次从该植物中分离得到。 Objective: To study the chemical constituents from Lobelia chinensis. Method: The constituents were extracted with 95% EtOH, partitioned with different solvents, and isolated and purified by silica gel column chromatography and crystallization, their structures were elucidated by physico-chemical properties and spectroscopic data. Result: Seven compounds were isolated from the titled plant. They were identified as 5-hydroxy-4′-methoxyflavone-7-O-rutinoside (1), n-butyl-O-β-D-fructopyranoside (2), 5,7-dimethoxycoumarin (3), cirsiumaldehyde (4), diosmetin (5), 5-hydroxymethyl-2-furancarboxaldehyde (6), and 6-hydroxy-7-methoxycoumarin (7). Conclusion: Compounds 2-4, 6, and 7 were obtained from the titled plant for the first time.
出处 《中国中药杂志》 CAS CSCD 北大核心 2009年第17期2200-2202,共3页 China Journal of Chinese Materia Medica
关键词 半边莲 全草 化学成分 Lobelia chinensis whole plants chemical constituents
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