摘要
目的比较真菌性鼻窦炎的临床诊断和真菌实验室诊断的差异。方法回顾100例真菌性鼻窦炎患者，根据临床表现、影像学检查及手术中所见作为临床诊断的标准，同时在术中取鼻窦黏膜送病理检查，鼻窦分泌物送真菌涂片镜检和培养。结果100例患者中，真菌球性鼻窦炎、变应性真菌性鼻窦炎、急性暴发性侵袭性真菌性鼻窦炎以及慢性侵袭性真菌性鼻窦炎分别是82例、10例、6例和2例。临床诊断、病理诊断、真菌涂片和培养的阳性率分别是95％、61％、78％和74％。上述检测方法的阳性率之间差异有统计学意义（P〈0．01）。结论临床诊断可以作为初步判断真菌性鼻窦炎的主要手段，特别是真菌球性鼻窦炎、变应性真菌性鼻窦炎以及急性暴发性侵袭性真菌性鼻窦炎。真菌性鼻窦炎的诊断需要结合临床诊断、病理检查、真菌涂片和培养，真菌培养是确定致病真菌的主要手段。
Objective To compare the differences between clinical diagnosis and laboratory diagnosis of fungal sinusitis. Methods One hundred cases of fungal sinusitis were reviewed in this study. The clinical characters including symptoms, physical signs, images and intraoperative signs were the main aspects of clinical diagnosis. The results of clinical diagnosis, pathology, direct observation of the nasal and sinus samples with microscope and the fungal culture were compared. Results The numbers of fungal ball, allergic fungal sinusitis, acute fulminant inrasive fungal sinusitis, and chronic invasive fungal sinusitis were 82, 10, 6, and 2 respectively. The positive rates of clinical diagnosis, pathology, direct observation with microscope and the fungal culture were 95%, 61%, 78%, and 74% respectively. There was significant difference among the positive rates of above methods （P 〈 0. 01 ）. Conclusion Clinical diagnosis can be used as the preliminary method for fungal sinusitis diagnosis. The demonstrative diagnosis needs to combine all above methods. The culture was the main method for confirm the types of pathogenic fungus.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2009年第32期2253-2256,共4页
National Medical Journal of China
基金
基金项目：科技部国家科技支撑计划资助项目（2007BA118815）
关键词
鼻窦炎
真菌
实验室技术和方法
Sinusitis
Fungi
Laboratory techniques and procedures
