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不同年龄组结直肠癌的临床病理特点 被引量:27

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摘要 目的:探讨不同年龄组结直肠癌(colorectal cancer,CRC)的临床病理特点。方法:回顾性分析910例CRC,以年龄为界划分为3组:青年组(≤35岁)、中年组(36~65岁)和老年组(>65岁),比较分析不同年龄组CRC的临床病理特征。结果:CRC中位年龄为19~92(67.00±12.86)岁,老中青患者分别占53.1%、44.9%和2.0%。中老年组肿瘤≥3cm者分别占74.1%和76.2%,较青年组明显增多(P=0.039)。青年组浸润型肿瘤占44.4%,老年组溃疡型达57.4%,各组肿瘤形态有明显不同(P=0.000)。青年组中、低分化肿瘤分别占55.6%和38.8%,远高于其他两组(P=0.008)。各组肿瘤发生部位(P=0.000)和分期(P=0.007)亦存在明显差异,青年组远端结肠癌占55.6%,且Duke′sB期和C期分别达到38.9%和44.4%。青年组血清CEA较其他两组明显升高(P=0.038)。结论:不同年龄组CRC的肿瘤大小、形态、发生部位、细胞分化、临床分期以及血清CEA水平等存在显著差异。青年组CRC确诊时往往临床分期较晚、肿瘤细胞分化程度较低、病理类型较差。
出处 《实用医学杂志》 CAS 北大核心 2009年第17期2897-2899,共3页 The Journal of Practical Medicine
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参考文献12

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