摘要
目的观察吉西他滨加卡培他滨治疗复发转移性乳腺癌近期疗效。方法吉西他滨加卡培他滨治疗27例复发转移性乳腺癌,同时观察其毒副作用。结果完全缓解1例,部分缓解18例,稳定5例,进展3例,总有效率为70.4%。主要毒副作用为手足综合症、骨髓抑制。结论吉西他滨联合卡培他滨治疗蒽环类耐药的复发转移性乳腺癌疗效较好,不良反应可以耐受。
Objective To observe the near futur effect of gemcitabine and capecitabine regimen treatment of patients with metastatic breast cancer. Methods 27patients with metastatic breast cancer were evaluated in gemcitabine and capecitabine regimen. Results 1 patient were CR, 18 patients were PR,5 patients was NC ,3patients were PD, total remission rate was 70.4%. The most effect was hand-foot syndrome, leukocytopenia. Conclusion This regimen shows more better for metastatic breast cancer,its toxic reaction are tolerable.
出处
《中国现代药物应用》
2009年第17期26-28,共3页
Chinese Journal of Modern Drug Application
关键词
吉西他滨
卡培他滨
乳腺癌
联合化疗
Gemcitabine
Capecitabine
Breast cancer
Combined chemotherapy
