摘要
目的:研究肾透明细胞癌发病机制与组织细胞凋亡的关系。方法:将标本离体后分成三组,(1)肾透明细胞癌组(根据肿瘤分期再分四组);(2)癌旁组织组;(3)正常肾组织组。用TUNEL法对标本检测。结果:在肾癌组织、癌旁组织及正常肾组织组均有凋亡发生。正常肾组织组细胞核有弱的阳性表达,癌旁组织表达明显增多,肾癌组织阳性表达最少。结论:细胞凋亡减少是肾透明细胞癌发生的重要机制之一。
Objective： Studying of the human renal clear cell carcinoma （RCCC） and the apoptosis Methods： Samples were divided into three groups： RCCC group （divided into four groups again by carcinoma period）, later carcinoma tissue group, and normal tissue group, studied by TUNEL method; Results： Apoptosis occurred in the renal carcinoma, later Carcinoma and normal renal tissues.. The expression was weakly positive in the nucleus of the normal renaI tissue and significantly increased in the later carcinoma tissue, while the expression was the most weakly in the RCCC tissue. Conclusions： Cell apoptosis reducing one of the important mechanisms in the human renal clear cell carcinoma.
出处
《中国医药导刊》
2009年第8期1333-1333,1335,共2页
Chinese Journal of Medicinal Guide
