期刊文献+

非甾体抗炎药致老年人消化性溃疡的临床特点分析 被引量:4

CLINICAL CHARACTERISTICS OF PEPTIC ULCER INDUCED BY NONSTEROIDAL ANTI-INFLAMMATORY DRUGS IN THE AGED
下载PDF
导出
摘要 目的:分析非甾体抗炎药(NSAIDs)所致的老年人消化性溃疡的临床特点。方法:收集本院2005年8月至2008年8月的老年人消化性溃疡出血住院患者的临床资料,根据出血前10d内是否服用过NSAIDs,将其分为两组进行比较分析。结果:NSAIDs组与非NSAIDs组溃疡类型、溃疡数目、临床症状等方面均有显著差异。结论:应加强对老年人使用NSAIDs所致消化性溃疡的临床特点的认识,并采取相应措施,减少NSAIDs的不良反应。 Objective :To investigate retrospectively the clinical characteristics of peptic ulcer induced by nonsteroidal anti-inflammatory drugs (NSAIDs) in the aged.Methods:168 patients with peptic ulcer bleeding from August 2005 to August 2008 were divided into 2 groups based on whether they had a recent history of taken NSAIDs.The clinical data were analyzed and compared.Results: There was significant difference between NSAIDs group and no NSAIDs group in types of ulcer, number of ulcer, and clinical symptom. Conclusion:It is important to get insight about the clinical characteristics of peptic ulcer induced by NSAIDs in the aged.Relevant measures should be taken to reduce the adverse effect of NSAIDs.
作者 唐来清
出处 《泸州医学院学报》 2009年第4期408-410,共3页 Journal of Luzhou Medical College
关键词 非甾体抗炎药 消化性溃疡 出血 Nonsteroidal anti-inflammatory drugs(NSAIDs) Peptic ulcer Hemorrhage
  • 相关文献

参考文献8

二级参考文献18

  • 1Kim JG, Graham DY. Helicobacter pylori infection and development of gastric or duodenal ulcer in arthritic patients receiving chronic NSAIDs therapy. The misoprostol study group. Am J Gastroenterol,1994, 89:203-207. 被引量:1
  • 2Wu CY, Poon SK, Chen GH, et al. Interaction between Helicobacter pylori and non-steroidal anti-inflammatory drugs in peptic ulcer bleeding. Scand J Gastroenterol, 1999,34:234-237. 被引量:1
  • 3Weil J, Colin-Jones D, Langnan M, et al. Prophylactic aspirin and risk of peptic ulcer bleeding. BMJ, 1995,310:827-830. 被引量:1
  • 4Soll A . Pathogenesis of non-steroidal anti-inflammatory drugs-related upper gastrointestinal toxicity. Am J Med, 1998,105 (SA) :10S-16S. 被引量:1
  • 5Cryer B, Redfem JS, Goldschmiedt M, et al. Effect of aging on gastric and duodenal mucosal prostaglandin concentrations in humans. Gastroenterology, 1992,102(4 Pt 1) :1118-1123. 被引量:1
  • 6Aalykke C, Lauritsen JM, Hallas J, et al. Helicobacter pylori and risk of ulcer bleeding among user of non-steroidal anti-inflammatory drugs: a case-control study. Gastroenterology, 1999, 116: 1305-1309. 被引量:1
  • 7Kuyvenhoven JP, veenendaal RA, vandenbrouke JP.Peptic ulcer bleeding:interaction between nonsteroidal anti - inflammatory drugs, Helieobacter pylori infeetion,and ABO blood group system. Seand J Gastroenterol, 1999,34 : 1 082~1 086. 被引量:1
  • 8All S Taha,Stephen Dahill,Christine Morran. Neutrophils, Helicobater phlori, and Nonsteroidal Anti - inflammatory Drug Ulcers。 Gastroenterology, 1999,116(2) ,245~258. 被引量:1
  • 9Voutilainen M, Sokka T, Juhola M. Nonsteroidal anti-inflammatory drug - associated upper gastrointestinal lesions in rheumatoid arthritis patients. Relationships to gastric histology, Helicobacter pylori infection, and other risk factors for peptic ulcer. Scand J Gastroenterol,1998 33(8), 811~816. 被引量:1
  • 10Aalykke C, Lauritsen JM, Hallas J. Helicobaeter pylori and risk of ulcer bleeding among users of nonsteroidal anti - inflammatory drugs:a case- control study.Gastroenterology. Jun, 1999,116 (6):1305~1309. 被引量:1

共引文献34

同被引文献15

引证文献4

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部