摘要
内源性气体分子一氧化氮(nitric oxide,NO)、一氧化碳(carbon monoxide,CO)和硫化氢(hydrogen sulfide,H2S)是具有广泛生物学效应的3种气体信号分子,由于他们具有舒张血管、抑制血小板聚集和抑制细胞增殖等生物功能,使得近几年来关于气体信号分子的研究逐步活跃起来,其在肝硬化门静脉高压中的作用已经逐渐引起人们的重视,现就此作一综述.
Nitrogen monoxide, carbon monoxide and hydrogen sulfide are three types of endogenous gas molecules that are able to exert diverse biological effects. As they can dilate blood vessels and suppress platelet aggregation and cell multiplication, the research on these gas signal molecules has become active. Their role in the development of hepatic cirrhosis with portal hypertension has gradually attracted more attention. Here, we will review the role of these gas signal molecules in the development of hepatic cirrhosis with portal hypertension.
出处
《世界华人消化杂志》
CAS
北大核心
2009年第19期1962-1966,共5页
World Chinese Journal of Digestology
基金
国家自然科学基金资助项目
No.30850004~~
关键词
气体信号分子
肝硬化
门静脉高压
Gas signal molecule
Hepatic cirrhosis
Portal hypertension
