摘要
目的探讨功能性消化不良(FD)的病因与心理、社会因素的关系,比较消化科常规治疗与抗抑郁、抗焦虑药对其的疗效。方法对80例FD病人进行抑郁自评量表(SDS)、焦虑自评量表(SAS)评分;再将80例FD患者随机分入对照组(常规消化科治疗)、黛力新(氟哌噻吨和美利曲辛)组(常规消化科治疗+黛力新),疗程均为8周,治疗后再进行上述量表评分,同时判断消化道症状的改善程度。结果FD患者SDS、SAS量表评分比中国常模的分数高,显示FD患者确有抑郁性情绪障碍和焦虑性情绪障碍。FD患者经抗郁抗焦虑药(黛力新)治疗8周后,消化道症状改善总有效率82%,较对照(61%)显著提高,且治疗前后SDS、SAS量表评分差异存在显著性(P<0.01)。结论FD与心理因素关系密切。FD患者普遍存在抑郁和焦虑情绪,用抗抑郁药联合抗焦虑药治疗FD能显著改善患者的症状,包括精神和躯体两方面的症状。
Objective To evaluate the ralation between the etiology of functional dyspepsia（FD） and psychological,compare the role of tranditiard therapy in digested sections with antidepressants and anxiolytic. Methods 80 FD patients were with SDS and SAS;then were divided into control term（ tranditional therapy）, deanxit （flupentixol and melitracen） term （common ther- apy ＋ deanxit）. 8 weeks later, the two terms evaluated with above-mentioned table and judge the degree of the improving in digested symptom. Results The mark with SDS and SAS of FD patients were higher than Chinese healthy people,which showed FD patients had anxiety and depression. With antidepressants and anxiolytic, total effective rate （ 82% ） was higher than comparison term, the mark between the before and after treatment has significant difference （ P 〈 O. 01 ）. Conclusion FD patients commonly have depression and anxiety. Antidepressants and anxiolytic can improve digested symptom in FD patients largely, including psyche and body.
出处
《临床消化病杂志》
2009年第4期215-216,共2页
Chinese Journal of Clinical Gastroenterology
