摘要
目的:探讨二切口与三切口食管癌切除胃代食管术疗效及生活质量。方法;我院自1980年7月至1991年12月行食管瘤切除胃代食管术594例,其中经左颈胸二切口464例,经右颈胸腹三切口130例。结果:三切口组术后并发症、死亡率明显高于二切口组(P〈0.05),术后1、3、5年生存率偏低于二切口组,无统计学意义(P>0.05)。但淋巴结阴性与阳性之间比较,5年生存率有极显著性差异(P<0.01)。两组术后生活质量比较,三切口组术后进食量、进食后胸闷不适、体重下降等3项指标与二切口组有显著性差异(P<0.05)。结论:出现以上结果的原因与三切口病历选择有关,胃代食管术对病人术后生活质量影响较大,三切口组更为明显。加强对早期食管瘤的诊断与治疗,是提高远期生存率的关键。
Objective investigation on postoperative effects and Living quality by taking two-cutand three-cut esophageal carcinoma resection with replacement of esophagus by stomach. Methods FromJuly 1980 to December 1991, 594 cases of esophageal carcinoma resection with stomach instead had beentaken in our hospital, which including 464 cases with two-cut through left check and chest as well as130 cases with three-cut through right check, chest and abdomen. Results Postoperative complicationand death rate were obviously higher in three-cut group than in two-cut group(p<0. 05). The survivalrate was lower in three-cut group in the-1,-3, -5year later, but there's no statistic meaning, (p>0. 05 ).However, significant differences appeared in the five year survival rate when compared positive withnegative of lymph node, (p<0. 01). Meanwhile, significant differences appeared at postoperative livingguality in such three targets as eaten amount, chest distress after eaten and lower weight, (p<0. 05).Conclusions The auther considers that the results are connected with how to choose the three-cut cases.The replacement of esophagus by stomach operation especially three-cut has much affect on patients' liv-ing quality. So the key to improve longterm survival rates is to strengthen diagnosis and treatment onpremature esophageal carcinoma.[
出处
《中国肿瘤临床与康复》
1998年第2期47-49,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
食管癌
胃代食管术
生活质量
治疗
esphageal carcinoma, replacement of esophagus by stomach, operative effect, livingquality