摘要
目的比较甲苯胺红不加热血清试验(TRUST)、螺旋体明胶颗粒凝集试验(TPPA)两种梅毒血清学试验的检测结果。方法将2008年至2009年二四二医院性病门诊138例确诊梅毒患者血清同时用甲苯胺红不加热血清试验(TRUST)、螺旋体明胶颗粒凝集试验(TPPA)检测,比较两种梅毒检测实验方法的灵敏度和特异性。结果138份血清中,98份血清TRUST阳性,17份经抗梅毒治疗血清TRUST阴性,TPPA试验133份血清为阳性。结论TRUST试验可作为梅毒的人群筛查、疗效、复发或再感染的检测指标,TPPA试验是检测梅毒螺旋体抗体的特异性方法,主要作为梅毒的确证试验。两种不同方法同时进行梅毒检测,将减少漏诊、误诊率,为梅毒的确诊提供参考依据,并且在判定梅毒的发展、痊愈及药物疗效方面都具有十分重要的意义。
Objective Compare the results of the two kinds of syphilis serological test, Namely, Toluidine red unheated serum test（TRUST） and Treponema gelatin particle agglutination test（TPPA）. Methods Tests made by No. 242 Hospital during 2008 -2009 and 138 cases of Syphilis using TRUST and TPPA, comparing sensitivity and specificityin the Syphilis Testing. Results 98 out ofthe 138 cases, blood serum show TRUST masculine, 17 show TRUST feminine after Anti -syphilis treatment. 133 blood serum is TPPA masculine. Conclusion TRUST Experi- ment can give Detection indicator of patients of syphilisin sorting, treating and relapse and re - infection. TPPA ex- periment is a methodof Detection of Treponema pallidum antibody. Mainly it serves as confirmatory test of syphilis. It plays an important partin diagnose of syphilis. Two methods was done simultaneouslyin Syphilis Testing, It will re- duce the rate of missed diagnosis and misdiagnosis. It will provide references or foundation to the diagnosis. It is im- portant todetermination of syphilis development,recovery and medical effect.
出处
《哈尔滨医药》
2009年第4期14-15,共2页
Harbin Medical Journal
