摘要
目的观察不同透析液钾浓度对血液透析患者血钾和心律的影响，总结钾浓度3．0mmol／L透析液的有效性和安全性。方法对我院50例尿毒症维持性血液透析患者先后应用钾浓度为2．0mmol／L（第一阶段）、3．0mool／L（第二阶段）的透析液各进行3个月血液透析，分别记录并比较临床症状及透析前和透析后血钾、心电图。结果第二阶段患者透析前和透析后血钾水平较第一阶段升高（P〈0．05），血液透析中心律失常发生率低于第一阶段[（第一阶段429例次，第二阶段137例次）]（P〈0．05）。两阶段透析前高血钾出现率无明显差异（P〉0．05）。结论钾浓度3．0mmol／L透析液能明显减轻血液透析中和血液透析后的低血钾，避免或减轻透析中心律失常的发生。透析间期未发现危及生命的高血钾症。使用钾浓度3．0mmol／L透析液预防血液透析相关心律失常有效、安全。
Objective To investigate the effect of dialysate potassium concentration on the serum potassium and arrhythmia during hemodialysis（HD） in patients with end-stage renal disease （ESRD）. Methods Fifty uremia patients undergoing maintenance hemodialysis were treated by dialysate of different concentrations of potassium ion in two periods of three months. Potassium ion concentration in the first period was 2.0 mmol/L, and 3.0 mmol/. L in the second period. Clinical symptoms, serum potassium and electrocardiogram before and after hemodialysis were recorded and observed. Results The serum K ＋ in B group was significantly higher than that in B group （P 〈 0.05）. The incidences of arrhythmia in B group decreased （ P 〈 0.05 ）. There was no significant difference of hyperkalemia between the two different HD treatments （ P 〉 0.05 ）. Conclusion The potassium density of 3.0 mmol/ L dialysate can avoid or decrease the occurrence of cardiac arrhythmia during dialysis. It is valid and safe for preventing cardiac arrhythmia when patients have hemodialysis three times a week.
出处
《中国医药》
2009年第9期685-686,共2页
China Medicine
关键词
血液透析
透析液
钾离子浓度
心律失常
Hemodialysis
Dialysate
Potassium concentration
Cardiac arrhythmia
