摘要
目的探讨单导植入式水冷微波电极不同功率与时间组合条件下消融猪后臀离体肌组织形成的凝固范围、形态及其影响因素。方法采用频率2450MHz微波,连续波作用方式,单导植入式内水冷却微波电极,采用40、50、60和70W4个功率,每个功率分别作用300s及600s。消融过程中监测热场周边温度变化。结果不同功率及不同时间消融的肌组织形态均为类球形,以50W消融的肌组织形态最接近球形。在相同作用时间下,随功率增加消融灶的体积增大,电极与肌纤维间角度及筋膜影响消融组织的形态和范围。消融靶目标外穿刺针道组织无损伤。热场边缘温度在58℃持续10s时组织无凝固性坏死。结论植入式内冷却微波消融肌组织的范围随作用功率和时间增大,消融区呈类圆形,沿穿刺针道外组织无损伤,本研究为临床微波消融子宫肌瘤提供实验依据。
Objective To evaluate the shape and size of microwave （MV） ablation of ex vivo muscular tissue and facts affecting ablation size by implanting water-cooling needle antenna with multiple power and time combination. Methods The MV frequency of 2450 MHz and single needle antenna with inner water-cooling devices were used. The mode of irradiation was continuous wave. The output power was set at 40,50,60 and 70 W. The ablation time was 300 s and 600 s respectively. The temperature of thermal field was detected by thermal couple while the MV was irradiating. Results In different output power and time combination, the ablated shape was mostly ellipsoid and spherical when the output power was set at 50 W. The diameter was enlarged along with an increase of the output power when the time was fixed. The ablated shape and volume were various with the angle between irradiator and muscle fiber or anadesma. The tissues on the needle track were not damaged by the MW ablation. The tissue was not coagulated when the tempera- ture was less than 58℃ and lasted less than 50 s. Conclusions The ablated size was enlarged with inereasing output power and time when the ablation was performed using a single needle antenna with internal water-cooling. The ablated zone was similar to a sphere. The tissues of needle track were not coagulated. The MW with internal water-cooling antenna could be safe for ablation of fibroid uterine.
出处
《中华医学超声杂志（电子版）》
2009年第4期22-25,共4页
Chinese Journal of Medical Ultrasound(Electronic Edition)
基金
解放军总医院苗圃基金(06MP57)
关键词
微波
平滑肌
肌组织肿瘤
消融
Microwaves
Smooth muscle
Muscle tissues neoplasms
Ablation
