摘要
目的了解血压正常男、女年轻人群(16～30岁)动脉功能参数:脉搏曲线分析指数[大动脉弹性指数(C1)和小动脉弹性指数(C2)]、颈股动脉脉搏波传导速度(cfPWV)和颈桡动脉脉搏波传导速度(crPWV)及其他生理指标之间的关系。方法入选血压正常志愿者共270例,年龄16～30岁,男性112例,女性158例,调查受试者基本资料,并采用CVProfilor DO-2020型动脉功能检测仪和脉搏波传导速度(PWV)测定仪分别测量C1、C2及cfPWV、crPWV。对动脉弹性指标和心血管疾病相关生理指标的关系进行分析。结果男性C1与身高、体质量呈正相关,与收缩压、平均动脉压(MAP)、脉压和心率呈负相关,其中与脉压相关性最大(r=-0.532,P<0.01);C2与收缩压、舒张压、MAP和心率呈负相关,其中与收缩压相关性最大(r=-0.319,P<0.01);cfPWV与舒张压和年龄呈正相关;crPWV与年龄、舒张压、身高和体质量呈正相关。女性相关关系与男性相似,其中C1和脉压相关性最大(r=-0.514,P<0.01),C2与心率的相关性最大(r=-0.552,P<0.01);cfPWV、crPWV均与舒张压、MAP、收缩压呈正相关,与舒张压相关性最大。结论血压、心率和肥胖相关指标是影响年轻人C1、C2的重要因素,舒张压对PWV产生影响。
Objective To investigate the vascular compliance markers （C1 and C2 ） and pulse wave velocity in relative with other physiological indexes in a cohort of young normotensive people in Beijing. Methods Two hun dred and seventy normotensive volunteers （ 112 men and 158 women aged 16 to 30 years） were invovled, completed questionnaires of demographic information. Large （C1 ） and small （C2） arterial compliance were derived from arterial pulse wave contour analysis. Pulse wave velocity（ carotid-femoral PWV and carotid-radial PWV） was determined by Complior SP. Results In both male and female C1 correlated positively with height and weight, and negatively with systolic（SBP）, mean arterial blood pressure（MAP）, pulse pressure（PP） , and heart rate（HR）, in which PP showed the best correlation with C1; C2 was inversely related with SBP, diastolic blood pressure（DBP）, MAP and HR, in which SBP showed the best correlation with C2 ; cfPWV correlated positively with DBP and age, crPWV correlated positively with age, DBP, height and weight. Conclusion Blood pressure, heart rate were the important influential factors of large and small arterial compliance in both males and females, while diastolic blood pressure was determinant for pulse wave velocity.
出处
《中华高血压杂志》
CAS
CSCD
北大核心
2009年第8期711-715,共5页
Chinese Journal of Hypertension
