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胃十二指肠良性疾病胃大部切除后远期随访观察

Long term follow-up of patients suffered from subtotal gastrectomy due to benign diseases of Gastroduodenal
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摘要 [目的]观察胃十二指肠良性疾病胃大部切除者的远期并发症、健康状况及与胃癌的关系,并探讨其手术指征。[方法]对66例因溃疡病、胃息肉、萎缩性胃炎等施胃大部分切除术后10年以上者进行随访复查,并对其并发症和目前健康状况作评估。[结果]66例均有不同程度的残胃炎,胆汁反流24例(36.3%),溃疡病10例(15.1%),营养不良9例(13.6%),贫血6例(9.1%),息肉和肠黏连各2例(3.0%),残胃癌3例(4.5%),食管癌1例(1.5%),大部分病例有1~3种重要并发症、合并症,生活质量明显下降。[结论]良性疾病作胃大部切除10年以上者,除均有残胃炎外,可并发胆汁反流、溃疡复发、营养不良等,发生癌变占6.1%。目前,对溃疡病等采用PPI治疗效佳、安全。因此,作胃大部切除的指征应严格掌握。 [Objective]To investigate the long term complications and health condition of patients suffered from subtotal gastrectomy due to benign diseases of gastroduodenal, especially the relationship between gastric carcinoma and long term complications , as well as to investigate the indications for surgery, [Methods]Re-examination including gastroscope was made in 66 patients suffered from subtotal gastrectomy more than 10 years due to ulcer disease, gastric polyp and atrophic gastritis , and the complications , coexisting conditions and their current health condition was estimated.[Results]Sixty six patients all suffered from gastric stump inflammation in varying degrees,including 24 cases of bile reflux gastritis (36. 3 %), 10 cases of ulcer disease (15. 1%), 9 cases of malnutrition(13.6%) ,6 cases of anaemia(9. 1%),2 cases of polyp and ankylenteron respectively(3.0%). 3 cases of gastric stump cancer(4. 5%) and 1 case of esophageal carcinoma (1.5 %). Most of the patients suffer from 1--3 significant coexisting conditions, and their quality of life declined. [Conclusion]Patients suffered from subtotal gastrectomy more than 10 years due to benign diseases of gastroduodenal will suffer from bile reflux gastritis ,ulcer recurring,malnutrition besides gastric stump inflammation , the occurrence canceration is 6. 1%, in addition to the coexisting conditions, the health condition is significantly influenced. As so far, patients suffering from ulcer disease treated with PPI has got a satisfied therapeutic effect. So the indications for surgery should be strictly controlled.
出处 《中国中西医结合消化杂志》 CAS 2009年第4期233-235,共3页 Chinese Journal of Integrated Traditional and Western Medicine on Digestion
基金 上海市奉贤区卫生局资助课题(200306)
关键词 胃肠疾病 胃大部分切除 远期随访 Gastroduodenal diseases subtotal gastrectomy long term follow-up
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