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血清抗GBM抗体对狼疮性肾炎早期诊断的意义 被引量:2

DETECTION AND SIGNIFICANCE OF ANTIGBM ANTIBODIES IN EARLY DIAGNOSIS OF LUPUS NEPHRITIS
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摘要 目的:探索狼疮性肾炎的早期诊断。方法:应用间接免疫荧光法测定43例SLE及23例健康人(对照组)血清抗GBM抗体。结果:SLE组血清抗GBM抗体阳性率显著高于对照组(P<001),在SLE抗GBM抗体阳性患者中80%发展成狼疮性肾炎(P<005)。结论:血清抗GBM抗体与狼疮性肾炎密切相关。 Objective:To seek early diagnosis of lupus nephritis.Methods:Serum antiGBM antibodies in 43 patients with SLE and in 23 normal people were examined by immunofluorescence microscopy.Results:The positive ratio of antiGBM antibodies were significantly higher in SLE patients than in controls (P<001).Most of SLE patients (80%) with positive antiGBM antibodies developed lupus nephritis (P<005).Conclusion:The antiGBM antibodies are related to lupus nephritis and taken as reference for early diagnosis.
出处 《中华风湿病学杂志》 CAS CSCD 1998年第2期106-107,共2页 Chinese Journal of Rheumatology
关键词 狼疮肾炎 诊断 抗体.抗GBM lupus nephritis diagnosis antibodies,antiGBM
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  • 1杨敏,张训.血管炎患者抗中性粒细胞胞浆抗体检测的意义[J].中华肾脏病杂志,1996,12(3):147-150. 被引量:10
  • 2曾清华,郑秀娟,温振科,徐林,于宁,徐薇,储以微,熊思东.一株抗双链DNA单克隆抗体的制备及其特性研究[J].现代免疫学,2007,27(3):193-197. 被引量:2
  • 3陆再英,钟南山.内科学[M].第七版.北京.人民卫生出版社,2008:463. 被引量:8
  • 4Hochbeyg MC. The 1997 Update of the 1982 American College of Rheumatology Revised Criteria for Classification of Systemic Lupus Erythematosus[J]. Arthritis Rheum, 1997 ,40:1725-1725. 被引量:1
  • 5Hellmark T, Niles JL, Collins AB, et al. Conparison of Anti-GBM antibodies in sera without ANCA[J]. Journal of the American Society of Nephrology, 1997,8:376. 被引量:1
  • 6Nicholls SJ, Hazen SL. Myeloperoxidase and cardiovascular disease [J]. Arterioscler Thromb Vasc Biol, 2005,25:1102-1111. 被引量:1
  • 7Suzuki K, Kobayoyhi, S, Yamazaki K, et al. Analysis of risk epitopes of anti-neutropil antibody MPO-ANCA in vascu litis in Japanese population[J]. Microbiology and immunology, 2007,51(12): 1215-1220. 被引量:1
  • 8Tan EM, Chan KEL, Sullivan KF, et al. Antineutrophil cytoplasmic autoantibodies: Diagnostically specific immune markers[J]. Clin Exp Immunol, 1998,47:121. 被引量:1
  • 9Short AK, Esnauh VL, Lock rood CM. Anti-neutrophil cytoplasm antibodies and anti-glome nlar hasemert membrane antibodies: twocoexisting distinct autoreactivities detectable in patierts uith rapidly progressivge glomeruloncphritis[J]. Am J Kidney Dis, 1995, 26:439-445. 被引量:1
  • 10Fmtos MA,Praga M,Quereda C,et al.Lupus nephriffs:in search of a better future[J].Nefmlogia,2012,32(2):136-138. 被引量:1

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