摘要
目的:探索狼疮性肾炎的早期诊断。方法:应用间接免疫荧光法测定43例SLE及23例健康人(对照组)血清抗GBM抗体。结果:SLE组血清抗GBM抗体阳性率显著高于对照组(P<001),在SLE抗GBM抗体阳性患者中80%发展成狼疮性肾炎(P<005)。结论:血清抗GBM抗体与狼疮性肾炎密切相关。
Objective:To seek early diagnosis of lupus nephritis.Methods:Serum antiGBM antibodies in 43 patients with SLE and in 23 normal people were examined by immunofluorescence microscopy.Results:The positive ratio of antiGBM antibodies were significantly higher in SLE patients than in controls (P<001).Most of SLE patients (80%) with positive antiGBM antibodies developed lupus nephritis (P<005).Conclusion:The antiGBM antibodies are related to lupus nephritis and taken as reference for early diagnosis.
出处
《中华风湿病学杂志》
CAS
CSCD
1998年第2期106-107,共2页
Chinese Journal of Rheumatology
关键词
狼疮肾炎
诊断
抗体.抗GBM
lupus nephritis diagnosis antibodies,antiGBM