摘要
目的:研究小剂量舒芬太尼复合丙泊酚用于无痛胃镜检查的麻醉效果。方法:ASAⅠ～Ⅲ级要求无痛胃镜检查的患者100例,年龄24～70岁,随机分为2组,即单纯应用丙泊酚组(A组)50例、复合小剂量舒芬太尼组(B组)50例,观察并记录检查前和给药后1、3、5 min患者平均血压(MBP),心率(HR),血氧饱和度(SpO_2)等生理指标的变化和出现的不良反应,及意识恢复时间、用量及不良反应。结果:A组与B组麻醉效果及氧饱和度(Sp_O2)无显著差异,各组给药后平均血压(MBP)、心率(HR)与给药前相比均有统计学意义(P<0.05),意识恢复时间A组与B组相比明显延长(P<0.05),用量A组比B组增加(P<0.05)。结论:复合小剂量舒芬太尼不仅可以减少丙泊酚用量,而且可以有效降低呼吸抑制副反应,缩短苏醒时间使麻醉更加平稳。
Objective： To observe the anesthesia effect of low-dose sufentanil composite application propofol for inspecting of painless gastrocopy. Methods： A hundred patients （24-70 years, ASAⅠ～Ⅲ） undergoing inspecting of painless gastrocopy were randomly divided into Propofol group （A group） （n = 50） and composite application of low-dose sufentanil group （B group） （n =50）. Monitoring indicators. The changes of hemodynamic （HR, MBP, SpO2）, the point times is base line, 1, 3, 5 rain after injecting drug; the dose of propofol, the mortality of adverse drug reaction, the recovery time of sense. Results： There were no statistic difference of anesthesia effect and SpO2 between the two groups （P 〉0.05）. The HR, MBP were less than the base line at the other 3 points of the two groups （P 〈0.05）. In the B group, the recovery time of sense and the dose of propofol were less than the A groups （P 〈0.05）. Conclusion： Composite application of low-dose sufentanil can reduce the dose of propofol, the side reaction of respiratory depression and shorten the recovery time, make the anesthesia process smooth.
出处
《新疆医科大学学报》
CAS
2009年第7期878-879,共2页
Journal of Xinjiang Medical University
关键词
胃镜
丙泊酚
舒芬太尼
gastrocopy
propofol
sufentanil
