摘要
目的:探讨高血压病患者中医证型与心血管危险因素之间的关系。方法:将300例高血压病患者按照中医辨证分型后作为观察对象(高血压组),40例健康人作为对照组。按调查表形式,以总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白-胆固醇(HDL-C)、低密度脂蛋白-胆固醇(LDL-C)、空腹血糖(FBG)、心电图等为客观指标,按照中医证型进行相关性分析。结果:家族史、体重指数(BMI)、吸烟、喝酒、TC、TG、LDL-C高血压组与健康组比较,差异均有显著性或非常显著性意义(P<0.05,P<0.01),HDL-C、FBG比较,差异无显著性意义(P>0.05)。高血压组各证型间比较,瘀血阻络组LDL-C明显升高;肝肾阴虚组高龄、TC正相关;痰瘀阻络组吸烟、年龄、TG正相关;痰火上扰组吸烟、喝酒、家族史、度型肥胖、BMI起标正相关;肝火亢盛组家族史病例明显增多,与其他证型比较,差异均有显著性意义(P<0.05)。结论:高血压中医证型与各心血管危险因素有一定相关性。
Objective:To investigate the correlation of TCM syndrome types in hypertension patients with risk factors of cardiovascular disease.Methods:Three hundred hypertension patients were enrolled into the study as the observation group,and 40 healthy volunteers served as the control group.The relationship of TCM syndrome types in hypertension patients with the parameters of total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),lowdensity lipoprotein cholesterol(LDL-C).and electrocardiogram(ECG) was analysed.Results: The differences of family history,body mass index(BMI),TC,TG and LDL-C were significant between the observation group and the control group(P<0.05 or P<0.01),but the differences of HDL-C and blood glucose level were insignificant(P>0.03).In hypertension patients, LDL-C was obviously increased in the syndrome of blood-stasis blocking collaterals;TC and advanced age were positively correlated with the syndrome of deficiency of liver and kidney;smoking, age and TG were positively correlated with the syndrome of phlegm and blood-stasis blocking collaterals;amoking,drinking,family history,abdominal obesity and over-standard BMI were positively correlated with the syndroene of upward flaming of phlegm-fire;the number of patients with hypertension family history increased obviously in the syadrome of hyperactivity of liver-fire (P<0.03 compared with that in other syndrome types).Conclusion:There is a certain correlation between TCM syndrome types in hypertension patients and risk factors of cardiovascular disease.
出处
《新中医》
CAS
北大核心
2009年第8期24-25,共2页
New Chinese Medicine
基金
国家重点基础研究发展(973)计划子项目(编号:2003CB517101)
