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国产阿立哌唑与利培酮治疗精神分裂症的对照研究 被引量:2

A controlled study on aripiprazole and risperidone in the treatment of schizophrenic outpatients
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摘要 目的探讨国产阿立哌唑治疗精神分裂症的疗效及不良反应。方法以国产阿立哌唑与利培酮治疗精神分裂症各30例作对照研究,采用阳性症状与阴性症状量表(PANSS)、治疗中出现的症状量表(TESS)评定疗效及不良反应。结果利培酮组有效率83.3%。显效率53.3%;国产阿立哌唑组有效率86.7%,显效率73.3%;国产阿立哌唑组无明显锥外系反应。结论两药治疗精神分裂症均有确切疗效,但国产阿立哌唑对精神症状的改善更明显。 Objective To research the therapeutic and side effects of aripiprazole in the treatment of schizophrenic patients. Methods Thirty schizophrenic patients were treated with risperidone as the controlled group. The efficacy was measured with the positive and negative symptoms scale( PANSS), while the adverse events were determined by the treatment emergent symptoms scale(TESS). Results The efficacy rate of Hsperidone was 83.3%, in which 53. 3% were improved markedly. The efficacy rate of aripiprazole was 86. 7% ,in which 73.3% were improved markedly. Conclusion It is suggested that both drugs are effective exactly in the treatment of schizophrenic patients. Aripiprazole appears to be more effective in improving psychiatric symptoms
出处 《四川精神卫生》 2009年第3期166-167,共2页 Sichuan Mental Health
关键词 阿立哌唑 利培酮 精神分裂症 Aripiprazole Rispefidone Schizophrenia
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  • 1Takeuchi H,Suzuki T,Uchida H,et al.A randomized,open-label comparison of 2 switching strategies to aripiprazole treatment in patients with schizophrenia:add-on,wait,and tapering of previous antipsychotics versus add-on and simultaneous tapering[J].J Clin Psychopharmacol,2008,28(5):540-543. 被引量:1
  • 2Kane TM,Carson WH,Saha AR,et al.Eficacy and safety of aripiprazole and halopeidol versus placebo in patients with schizophrenia and schizoafective disorder[J].J Clin Psychiatry,2002,63(7):763-771. 被引量:1
  • 3中华医学会精神科学会,中国精神障碍分类与诊断标准第三版(CCMD-3)[M].济南:山东科学技术出版社,2001:87—89. 被引量:6
  • 4Kane JM,Assuncao-Talbott S,Eudicone JM,et al.The efficacy of aripiprazole in the treatment of multiple symptom domains in patients with acute schizophrenia:a pooled analysis of data from the pivotal trials[J].Schizophr Res,2008,105(1-3):208-15. 被引量:1
  • 5童建明,杨正春.几种新型抗精神病药介绍[J].临床精神医学杂志,2005,15(3):182-182. 被引量:147
  • 6王刚平,颉瑞,裴根祥,张永录.阿立哌唑的临床应用(一)——阿立哌唑与氯氮平治疗精神分裂症对照研究[J].临床精神医学杂志,2006,16(1):44-45. 被引量:43

二级参考文献14

  • 1黄文武,姜德国.抗精神病新药阿立哌唑[J].上海精神医学,2003,15(5):307-308. 被引量:153
  • 2吴仁容,李乐华.新型抗精神病药:阿立哌唑[J].国外医学(精神病学分册),2004,31(3):177-179. 被引量:380
  • 3喻东山.老年精神分裂症的药物治疗[J].临床精神医学杂志,2004,14(5):304-306. 被引量:98
  • 4Potkin SG,Saha AR,Kujawa MJ,et al.Aripiprazoe,an antipsychotic with a novel mechanism of action with psychizophrenia and schizoaffective disorder[J].Arch Gen Psycheiatry,2003,60:681-690. 被引量:1
  • 5Kane TM,Carson WH,Saha AR,et al.Efficacy and safety ofaripiprazole and haloperidol versus placebo in patients with schizophrenia and schizoaffective disorder[J].J Clin Psychiatry,2002,63:763-771. 被引量:1
  • 6久住一郎,小山司.抗精神病藥の開發動向と問題点[J].臨床精神醫學,2004,263-267. 被引量:1
  • 7Bowles TM, levin GM. Aripiprazole : A new atypical antipsychotic drug [ J ]. Ann pharmacother, 2003,37 : 687-694. 被引量:1
  • 8Murasaki M. AD-5423 versus haloperidol in the treatment of schizophrenic patients: results of the Japan multicentle, double-blind trial [ J ]. Eur Neuropsychopharmacol, 2002,12 : 5268. 被引量:1
  • 9Gunasekara NS, Spencer CM, Keating GM. Ziprasidone : a review of its use irt schizophrenia and schizoaffective disorder[ J ]. Drugs, 2002,62 :1217-1251. 被引量:1
  • 10堀澤智子,田頭利惠,藪内一輝,ほか.新規抗精神病藥SM-13496の藥理學的特性:腦内各種受容體にすと作用評價[J].日本神經精神藥理學雜志,1999,19;363. 被引量:1

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