摘要
用一个新的氨基醇（１Ｒ，２Ｓ）－２－氨基－３－甲基－１－（２，５－二甲基苯基）－１－丁醇为手性配体，硼烷为还原剂，研究了２，２′，４′－三氯苯乙酮和２－咪唑基－２′，４′－二氯苯乙酮的对映选择还原。并讨论了催化剂用量、温度对还原效果的影响。
A new amino alcohol (1R,2S)2amino3methyl1(2,5dimethyl phenyl)1butanol, as a chiral ligand, was used in the enantioselective reduction of 2,2′,4′trichloroacetophenone and 2imidazol2′,4′dichloroacetophenone.The effect of the amount of catalyst and reaction temperature on enantioselectivity of the reduction were discussed.
出处
《西北农业大学学报》
CSCD
北大核心
1998年第3期32-34,共3页
Journal of Northwest Sci-Tech University of Agriculture and Forestry（Natural Science Edition)
关键词
手性氨基醇
硼烷
对映选择还原
chiral amino alcohol,borane,enantioselective reduction
