摘要
目的建立滑膜炎片的质量标准。方法采用薄层色谱法鉴别丹参、川牛膝,并采用HPLC法测定原儿茶醛的含量。结果薄层色谱图斑点清晰,阴性无干扰;原儿茶醛对照品进样量在0.021～0.105μg范围内线性关系良好,r=0.9999,平均回收率为98.13%,RSD为2.41%。结论该方法准确、灵敏、重现性好,可用于滑膜炎片制剂的质量控制。
Objective To establish the quality standard for Huamoyan Tablet. Methods Radix Salviae Mihiorrhizae and Radix Cyathulaewere were identified by TLC. The content of protocatechuic aldehyde was determined by HPLC. Results The spots on TLC plates were clear without the interference of negative control. Protocatechuic aldehyde showed a good linear relationship in the range of 0. 021 -0. 105μg, r =0. 999 9. The average recovery was 98.13 % , and RSD = 2.41%. Conclusion The method is simple, sensitive and accurate, and can be used to control the quality of Huamoyan Tablet.
出处
《中药新药与临床药理》
CAS
CSCD
北大核心
2009年第4期366-368,共3页
Traditional Chinese Drug Research and Clinical Pharmacology
关键词
滑膜炎片
丹参
川牛膝
原儿茶醛
TLC
HPLC
Huamoyan Tablet
Radix Salviae Miltiorrhizae
Radix Cyathulae
Protocatechuic aldehyde
TLC
HPLC
