摘要
目的探讨替罗非班在急性下肢动脉栓塞治疗的应用效果。方法总结和分析2005年1月至2008年9月收治的64例急性下肢动脉栓塞患者的临床资料:均采用导管介入方法吸取血栓,介入配合替罗非班治疗33例,对照组31例,观察两组治疗效果的差异。结果64例下肢动脉急性栓塞患者均采用介入方法成功去除大部分栓子,开通主干动脉。替罗非班治疗组术后再次血运重建率、截肢(趾)率、病死率均低于非替罗非班组,两组差异有统计学意义,且无严重出血发生。结论替罗非班配合介入治疗急性下肢动脉栓塞疗效好,且用药安全性较好。
Objective To observe the effect of platelet GP Ⅱ b/Ⅲ a antagonist tirofiban during the treatment of patients with acute arterial embolism. Methods 64 patients with acute arterial embolism were divided in two groups,31 patients in control group were not treated with Tirofiban,while 33 patients in experimental group are treated with Tirofiban. All patients were treated with interventional therapy. Results most thrombus in 64 patients was wiped off through tnterventional therapy. In contrast with control group, the incidences of target lesion revascularizaton, mortality, leg-cutting off were lower. And the incidence of hemorrhage was comparable. Conclusion Tirofiban is effective in the patients with acute arterial embolism when accepted interventional therapy, and it is a safe drug.
出处
《中国实用医药》
2009年第5期51-53,共3页
China Practical Medicine
关键词
下肢动脉急性栓塞
介入治疗
替罗非班
治疗效果
Acute arterial embolism
Tirofiban
Interventional therapy
Treatment outcome
