摘要
从GenBank下载1277条广州管圆线虫的表达序列标签(EST),用BlastX比对分析,并用SignalPV3.0预测潜在的抗原或过敏原相关蛋白N端是否具有分泌信号肽或信号锚定肽。结果显示,得分值>100有614条,其中14条与广州管圆线虫一致,540条与其他物种的相关蛋白相匹配,60条与数据库中序列无同源性。614条序列可分为10类,抗原或过敏原相关蛋白有80条,编码22种蛋白,其中12种具有分泌信号肽,3种具有信号锚定肽。
A total of 1 277 ESTs of Angiostrongylus cantonensis were downloaded from GenBank and analyzed with BlastX. SignalP V3.0 analysis was applied to predict potential putative antigen or allergen relative proteins with Nterminal secreted signal peptides or signal anchors. BlastX analysis showed that there were 614 ESTs scored more than 100, of which 14 were identical with A. cantonensis, 60 ESTs did not match any proteins in the databases. The identified 614 ESTs could be grouped into 10 categories, 80 ESTs expressed 22 antigen or allergen relative proteins, in which 12 had N-terminal secreted signal peptides and 3 had signal anchors.
出处
《中国寄生虫学与寄生虫病杂志》
CAS
CSCD
北大核心
2009年第3期248-250,共3页
Chinese Journal of Parasitology and Parasitic Diseases
基金
福建省科技计划项目(No.2008N2005)
厦门市科技计划项目(No.3502Z20074036)~~
