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不动杆菌的临床分布及耐药性分析

DISTRIBUTION AND RESISTANT PROFILE ANALYSES OF ACINETOBACTER IN SOUTHERN CHINA DISTRICT IN 7 YEARS
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摘要 目的了解不动杆菌的分布及其对常用抗菌药物的耐药性。方法应用回顾性调查分析方法对从2002年1月~2008年12月中山市博爱医院及清远市人民医院临床送检标本中分离的不动杆菌的药敏试验结果进行统计分析。结果不动杆菌对亚胺培南、环丙沙星、左旋氧氟沙星、庆大霉素、头孢吡肟、哌拉西林/他唑巴坦、氨苄西林/舒巴坦、妥布霉素较敏感,耐药率在15%以下,而对头孢噻肟、氨苄西林、头孢唑林、呋喃妥因耐药严重,耐药率在90%以上,其余抗生素耐药率在20%~80%之间。结论不动杆菌对常用抗生素有不同程度的耐药,临床应根据药敏试验结果合理用药,对提高感染治愈率及减缓多重耐药菌株的出现有重大意义。 Objective To analyze the distribution and resistance profile of acquired infections of Acinetobacter. Methods The distribution and the drug resistance patterns of Acinetobacter isolated fi'om clinical samples in Boai Hospital of Zhongshan and QingYuan city people' s hospital, from Jan 2002 to Dec 2008, were studied retrospectively. Results The Acinetobactor were sensitive to impenem, ciprofloxacin, levofioacin, gentamicin, cefepime, cefopera - zone/sulbactam, ampicillin/sulbactam, and tobramyein, the drug resistance was less than 15% ;Yet they were resistant to ampicillin, cefazolin, cefotetan, nitrofurantoin, the drug resistance was higher than 90%, that of the other antibiotics was range from 20% to 80%. Conclusions All Acinetobacter strains had drug re- sistance in some degree. It' s necessary to strengthen the clinic monitoring and select reasonable antibiotic in order to improve curative effect and delay bacterial of multi - resistance to antibiotic agents.
出处 《现代医院》 2009年第8期77-79,共3页 Modern Hospitals
关键词 不动杆菌属 感染 抗生素 耐药性 Acinetobacter, Infection, Antibiotic, Drug resistance
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