摘要
目的探讨^99Tc^m-MIBI SPECT—CT同机图像融合技术对于乳腺肿瘤显像及淋巴结转移判断的临床应用价值。方法对80例女性乳腺肿块患者行^99Tc^m-MIBI乳腺及腋窝淋巴结平面显像及^99Tc^m-MIBI SPECT—CT显像。所有患者均有手术后病理检查结果做对照。结果80例患者中SPECT—CT融合图像对乳腺癌诊断的灵敏度88．2％（45／51），高于平面显像的82．4％（42／51），两者差异有统计学意义（P〈0．05）。SPECT—CT融合图像对原发性乳腺癌诊断的特异度、准确度分别为93．1％（26／29）、90％（71／80），均高于平面显像的793％（23／29）、81．3％（65／80）。平面显像检测腋淋巴结的灵敏度77．2％（17／22），特异度86．2％（25／29），准确度82．4％（42／51），SPECT—CT融合图像检测腋淋巴结的灵敏度81．8％（18／22），特异度89．7％（26／29），准确度86.3％（44／51）。两者比较差异无统计学意义（P〉0．05）。结论SPECT—CT图像融合显像技术在乳腺癌诊断的灵敏度、特异度和准确度均高于平面显像。在乳腺癌腋窝淋巴结转移探测方面SPECT／CT罔像融合与平面显像相似。
Objective To investigate the clinical value of ^99Tc^m-MIBI SPECT-CT image fusion technology for diagnosing breast tumor and detecting axillary lymph node metastasis. Methods ^99Tc^m-MIBI breast and axillary lymph node planar and SPECT-CT imaging in 80 female breast tumor patients were done. All patients had pathological examination results after surgery as control. Results SPECT-CT fusion images sensitivity for breast cancer diagnosis, specificity and accuracy rates were 88.2 % （45/51）, 93.1% （26/29） and 90 % （71/80）. Planar imaging sensitivity, specificity and accuracy rate were 82.4 % （42/51）, 79.3 %（23/29） and 81.3 %（65/80）. SPECT-CT fusion images were higher than planar imaging （P 〈0.05）. SPECT-CT fusion images sensitivity, specificity and accuracy for detecting axillary lymph node metastasis were 81.8 %（18/22）, 89.7 % （26/29） and 86.3 % （44/51）. Planar imaging sensitivity, specificity and accuracy were 77.2 % （17/22）, 86.2 % （25/29） and 82.4 %（42/51）. There was no significant difference between them （P 〉0.05）. Conclusion SPECT-CT image fusion technology in the diagnosis of breast cancer is better than planar imaging. SPECT-CT image fusion in detecting axillary lymph node metastasis of breast cancer is similar to planar imaging.
出处
《肿瘤研究与临床》
CAS
2009年第7期455-457,共3页
Cancer Research and Clinic
