摘要
Objective To explore the remote efficacy and safety of consciousness-restoring resuscitation （Xingnao Kaiqiao, short for XNKQ） acupuncture on cerebral infarction at recovery phase. Methods Two hundred and thirty-four cases of cerebral infarction at recovery phase were randomized into XNKQ group and routine acupuncture group （routine group） in light of SAS code. One hundred and sixteen cases in the XNKQ group were treated with XNKQ acupuncture （once a day, totally 4 weeks） and routine treatment with western medicine. One hundred and eighteen cases in the routine group received routine acupuncture and routine treatment with western medicine. Follow-up lasted 6 months. Primary indexes： the situations of survival, treatment and recurrence at the end of follow-up. Secondary indexes： assessment of nerve functions at the end of follow-up and rate of adverse events during acupunc- ture. Results In 6 months follow-up, the mortality was 0.86% and rate of continuous treatment was 36.21% in the XNKQ group and they were 1.69% and 36.44% respectively in the routine group. The differences did not present statistical significance between the two groups （X^2 = 0.29, P=0.59; X^2 = 0.32, P = 0.57）. Concerning to the decrease of recurrence rate and improvement of nerve functions, the out-comes in the XNKQ group were superior to those in the routine group （P〈0.01）. Severe adverse events did not happen in the two groups. Conclusion XNKQ acupuncture is safe therapy and its remote efficacy is superior to that of routine acupuncture in the decrease of recurrence rate and improvement of nerve functions.
目的:探讨醒脑开窍针刺治疗脑梗死恢复期的远期疗效及安全性。方法:脑梗死恢复期患者234例,以SAS编码,随机分配到醒脑开窍针刺组和常规针刺组(简称醒脑组和常规组)。醒脑组116例,接受醒脑开窍针刺(每日1次,共4周)和西医常规治疗;常规组118例,接受常规针刺和西医常规治疗。随访6个月。主要指标:随访期末生存、治疗和复发情况。次要指标:随访期末神经功能评估,针刺过程中不良事件发生率。结果:6个月随访时醒脑组病死率(0·86%)、继续治疗率(36·21%)与常规组(1·69%、36·44%)差异无统计学意义(χ2=0·29,P=0·59;χ2=0·32,P=0·57) ,在降低复发率、改善神经功能方面醒脑组优于常规组(P<0·01) ;两组均未出现严重不良反应。结论:醒脑开窍针刺是安全的,其远期疗效在降低复发率、改善神经功能方面优于常规针刺。
基金
Supported by National 973 Project of China (2006CB504504)
Tianjin Municipal Key Technologies Research Program(05YFGDSF02300)
