摘要
特发性血小板减少性紫癜（ITP）是一种获得性的自身免疫性疾病，其特点为血小板数目减少和皮肤黏膜出血。目前认为自身抗体致敏的血小板被单核巨噬细胞系统过度吞噬破坏是ITP发病的主要机制。近来越来越多的证据表明，HIV和肝炎病毒等病毒以及幽门螺杆菌的感染与ITP的发病也有密切关系。此外，脾功能亢进以及雌激素等也与ITP的发病有关。
Idiopathic thrombocytopenic purpura （ITP）is an acquired autoimmune disorder, which is characterized by decreased platelet and bleed of skin and mucosa. At present, autoantibody-sensitized platelet destruction by mononuelear phagocytic system is thought to be the major mechanism of ITP. Recently, more and more evidences showed that infection with viruses such as HIV and hepatitis virus and Helicobacter pylori was also related to ITP. In addition,hypersplenism and estrogen are related to ITP too.
出处
《医学综述》
2009年第15期2304-2306,共3页
Medical Recapitulate
