极晚抗原4拮抗剂与西罗莫司联合应用对大鼠移植心脏存活时间的影响
被引量：1
摘要
作为目前免疫抑制方案的主体，钙调磷酸酶抑制剂（CNI）的。肾毒性日益受到关注。因此我们亟待建立一种不含CNI的新型免疫抑制方案，在有效预防急性排斥反应的同时，避免对移植肾的慢性毒性损害。极晚抗原4（VLA-4）拮抗剂WAY-160279和西罗莫司（SRL）是新型非CNI类药物，已证明有较强免疫抑制作用而无肾毒性。
出处
《中华器官移植杂志》
CAS
CSCD
北大核心
2009年第7期434-436,共3页
Chinese Journal of Organ Transplantation
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