摘要
研究了以对二甲氨基苯甲酸为原料,通过酰氯化反应,再和5-甲基-2-甲氨基苯硫酚进行缩合反应合成硫代黄色素T。产品的总收率大于75%。
The synthesis of thioflavine T was studied using p-dimethylaminobenzoic acid as material through chloroformylation reaction, and then by the condensation reaction with 5-methyl-2-methylaminothiophenol. The overall yield of the product was 75%.
出处
《应用化工》
CAS
CSCD
2009年第6期919-920,共2页
Applied Chemical Industry
关键词
对二甲氨基苯甲酸
酰氯化反应
5-甲基-2-甲氨基苯硫酚
缩合反应
黄色素T
合成
p-dimethylaminobenzoic acid
chloroformylation reaction
5-methyl-2-methylaminoth-iophenol
condensation reaction
thioflavine T
synthesis
