摘要
目的：最适红细胞压积（Ｈｏ）对于判定人体高原适应的优劣以及评定高原红细胞增多的生理及病理范围增多有意义；方法：对海拔３４１７到４２８０ｍ地区的世、移居人群作出Ｈｃｔ分布曲线，再建立Ｈｂ与ＰａＯ２、Ｈｃｔ与ＳａＯ２、Ｈｃｔ与ＣＯｍａｘ、Ｈｃｔ与ＶＯ２ｍａｘ及Ｈｃｔ与全血粘度的相关关系，以确定Ｈｃｔ在提高血氧水平、提高氧传送能力及供氧后最大功效上的最适位置；结果：世居藏族的Ｈｏ为０．４５～０．４８Ｌ／Ｌ，移居汉族０．５０～０．５２Ｌ／Ｌ，仍处于适度位点。Ｈｃｔ＞０．６０Ｌ／Ｌ时对人体已不再有利，＞０．６５Ｌ／Ｌ进入病理范围，＞０．７５Ｌ／Ｌ为危险信号；结论：Ｈｏ值可作为高原血液生理适应的一个标志，也有助于确立ＨＡＰＣ诊断标准的依据。
Objective:At high altitude,the erythrocythemia as a adaptive response to hypoxia,however,physiological and excessive polycythemia must be distingushed.The “optimum” of Hct should be established.Methods:The distribution of Hct in Tibetan natives and Han immigrants at elevations between 3 714m and 4 280m were surveyed,the relationship between Hb and PaO2,Hct and SaO2,Hct and COmax,Hct and VO2max as well as Hct and blood viscisity were studied.Results:The distribution of Hct in Tibetan natives showed that the main peak(045～052L/L) represents the physiological Hct for that altitude and that the secondary peak(060～065L/L) is excessive because persons with Hct of 065L/L are usually symptomatic.According to the levels of PaO2,SaO2,Comax and VO2max with Hct values ,the Ho in Tibetans are 045～048L/L compared with the Han immigrants of 050～052L/L.Conclusions:Ho not only a remaker of hypoxic adaptation,but may also hely in the better understanding of the haematological effects in the oxygen transport.
出处
《高原医学杂志》
CAS
1998年第2期1-4,共4页
Journal of High Altitude Medicine
