摘要
目的:以冠状动脉造影(CAG)为金标准,评价腺苷负荷超声心动图(ASE)试验诊断冠心病(CHD)的敏感性和特异性。方法:40例临床疑诊CHD患者,分别静脉注射腺苷(140μg·kg-1.min-1)6min(总剂量为0.8mg/kg)。出现节段性室壁运动异常为阳性。所有患者1周内行CAG检查。结果:ASE诊断CHD的敏感性为82.6%,特异性为88.2%,准确性为85.0%;诊断单支、双支和3支冠状动脉病变的敏感性分别为75.0%,85.7%,100%,且不良反应少。结论:ASE诊断CHD安全可靠。
Objective： To assess the value of adenosine stress echocardiography in diagnosis of coronary artery disease（CAD） and to determine the sensitivity and specificity according to CAG. Method： Adenosine was injected in 40 suspectable patients with coronary artery disease with total dose of 140 μg · min ^-1 · kg^-1 in 6 rain. Positive criterion was defined as the appearance of regional wall motion abnormality. CAG was performed within 1 week. Result： The sensitivity of adenosine stress echocardiography was 82.6 %, the specificity was 88.2 %, the accuracy was 85.0%. The sensitivity for detection of myocardial isehemia in one, two and three-criminal vessel were 75.0%, 85.7%, 100% （4/4）, respectively. Side effects due to adenosine infusion were always minimal. Conclusion： Adenosine stress echocardiography can be safely performed in suspectable CAD patients with high sensitivity and specificity.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2009年第7期547-549,共3页
Journal of Clinical Cardiology
关键词
冠状动脉疾病
腺苷
负荷超声心动图
诊断
coronary disease
adenosine
stress echocardiography
diagnosis
