摘要
目的观察麻醉前给予盐酸戊乙奎醚对小儿全麻苏醒期躁动的影响。方法100例患儿随机分为盐酸戊乙奎醚组（观察组）和阿托品组（对照组），每组50例，于术前30min分别肌内注射盐酸戊乙奎醚（0．01mg／kg）和阿托品（0．01mg／kg），术后观察两组患儿苏醒期的躁动情况，并进行比较。结果对照组组躁动率为14％（7／50），观察组躁动率为2％（1／50），两组患儿术后苏醒期躁动率间差异有统计学意义（P〈0．05）。盐酸戊乙奎醚组未发现心悸和视物模糊等不良反应。结论盐酸戊乙奎醚可减少小儿全麻苏醒期躁动的发生，不良反应发生轻，是术前用药中较为理想的抗胆碱药。
Objective To investigate the effects of penehyclidine hydrochloride in pre-medication on restlessness in children during the awaking stage of general anesthesia. Methods 100 patients were randomly divided into penehyelidine hydrochloride group （ n = 50 ） and atropine group （ n = 50 ）, they were received intramuscular injection with penehyclidine hydroehloride（0.01 mg/kg） or atropine（0.01 mg/kg） respectively,and then to compare the occurrence of restlessness during the awaking stage of general anesthesia. Results The incidence of restlessness in atropine group was 14% （ n = 7 ）, while the incidence of restlessness in penehyclidine hydrochloride group was 2% （ n = 1 ）, there were significant difference between two groups （ P 〈 0.05 ）. In penehyclidine hydrochloride group, there were no side effects such as palpitation and blur vision. Conclusion Penehyclidine hydrochloride reduces the incidence of restlessness in children and had little and light side effects, which could severe as a better preanesthetic medication.
出处
《医学综述》
2009年第14期2228-2229,共2页
Medical Recapitulate
关键词
盐酸戊乙奎醚
阿托品
小儿
躁动
Penehyelidine hydrochloride
Atropine
Children
Restlessness
