摘要
1989年3月至1992年3月,收治首程根治性放疗鼻咽癌389例,其中1期5例,Ⅱ期22例,Ⅲ期201例,Ⅳ期161例。Ⅲ~Ⅳ期占93.1％。全部采用~60Co外照射。总剂量DT68GY^DT72GY。总剂量中一半以面颈联合野照射,其余面颈分野照射。结果：全部病人随访5年以上,随访率91.5％;全组5年生存率48.1％;I~Ⅳ期5年生存率分别为80％、81.8％、57.2％、30.4％;5年内鼻咽／颈结复发率17.7％,复发病例88.3％在放疗后3年内;死亡202例中,明确死因为164例,其中64％死于远处转移,死于复发占22％。结论：T／N分期愈晚,预后愈差。失败原因主要为远处转移及复发。早期发现和治疗病人是提高鼻咽癌治愈率的关键。
An analysis of 389 patients with biopsy - proven nasopharyngeal careinoma (npe) treated by 60Co radiotherapy was conducted. There were 5, 22, 201 and 161 Patients with stage I,Ⅱ,Ⅲ, Ⅳ respetively. Patients with stage Ⅲ- Ⅳ accounted for 93. 1 %. All patients underwent external irraadiation by using 60 Co with the dose between 68GY and 72GY. The majority of patients were given half dose of Cheek - Neck combination field irradiation. The follow - up rate was 91.5%. The 5 - year overall survivalrate was 48.1%, The 5 - year survivalrate of stage I, Ⅱ,Ⅲ, Ⅳ, were 80%, 81 .8%, 57.2%, 30.4%, respectively. Nasopharyngealand neck node relapse rate was 17.7% within 5 year, 88.3% of recurrencecase happened within three years after radiotherapy. Among the patients who died after radiotherapy, 64% died from distant metastasis and 22% from local - regional recurrence. It is concluded that T and N stages are the moot significant prognostic factors in npc patients. Early detection, early diagnosis and earlytreatment are the key measures for improving long - term survival.
出处
《汕头大学医学院学报》
1998年第2期7-9,共3页
Journal of Shantou University Medical College
关键词
鼻咽癌
放射疗法
疗效
Radiotherapy
Nasopharyngeal Carcinoma
