摘要
目的:研究急性心肌梗死直接经皮冠脉成形术(PCI)住院死亡的独立危险因素。方法:回顾分析2004年9月—2007年12月急性心肌梗死直接PCI372例患者的临床资料。采用多元Logistic回归分析方法进行分析。结果:影响急性心肌梗死直接PCI术后住院期间的病死率的5个独立危险因素依次为:术前Killips>1级[比数比(OR)=7.17,95%可信区间(CI)=1.637～31.408,P=0.009;肌酐≥100μmol.L-1(OR=12.071,95%CI=2.502～58.222,P=0.002);恶性心律失常(OR=14.831,95%CI=2.475～88.865,P=0.003);心源性休克(OR=38.275,95%CI=7.968～183.869,P<0.001);非梗死血管狭窄≥70%(OR=5.578,95%CI=1.057～29.430,P=0.043)。结论:研究显示有5个独立因素(术前Killips>1级、肌酐≥100μmol.L-1、发生恶性心律失常、发生心源性休克及非梗死血管狭窄≥70%)影响急性心肌梗死直接PCI患者住院病死率。
Objective： To explore the independent risk factors of in hospital mortality for patients with the primary percutaneous coronary intervention（PCI） in acute myocardial infarction. Methods： Clinical data of patients underwent PIC due to acute myocardial infarction in our hospital from September 2004 to December 2007 was analyzed retrospectively. Multivaliate logistic regression models were used to find the independent risk factors. Results： Totally 372 eligible patients were included in this study. There were five independent risk factors affect the primary PCI in acute myocardial infarction mortality in hospital, preoperative killips〉 1 level, creatinine ≥ 100, malignant arrhythmia, cardiogenic shock and non-infarct artery stenosis≥70 %, the odd ratio（OR）and 950/oo confident interval（95%CI）were 7.17 （1.64-31.4） ,12.1（2.5-58.2） ,14. 8（2.5-88.9） ,38.3（8.0-183.9）and 5.6（1.1-29.4） ,respectively. Conclusion： The study indicated that five independent factors （preoperative Killips） 1 level, creatinine≥100, the occurrence of malignant arrhythmias, the occurrence of cardiogenic shock and non-infarct artery stenosis≥70%） the impact of the hospital mortality with the acute myocardial infarction patients for primary PCI.
出处
《中国临床医学》
2009年第3期335-337,共3页
Chinese Journal of Clinical Medicine
