摘要
目的:研究肝癌,肺癌患者凝血机能的改变。材料和方法:对50例拟行介入治疗的肝癌,肺癌患者介入治疗前行体外血栓形成试验,血小板粘附、聚集试验,及纤维蛋白原,血粘度,红细胞偶然性聚集性及刚性等指标的检测(并选100例正常献血员作为正常对照)。结果:肝癌,肺癌患者体外血栓长度,湿重,干重均较正常人增加(P<0.001);血小板粘附率,聚集率均较正常增高;全血粘度,红细胞聚集指数,刚性指数均有明显增高;纤维蛋白原定量亦增加(P<0.001)。结论:肝癌、肺癌患者介入治疗前血液即处于高凝状态,其有明显的血栓形成趋势,这就为肝癌、肺癌患者在介入治疗过程中配合抗凝及活血化阏治疗提供了理论依据,同时也是评价介入治疗疗效的一个重要指标。
Purpose:To evaluate the coagulative function of patients with HCC or pulmonary carcino- ma before interventional therapy.Material and Method:The experiments on the formation of thrombus, adhensiveness and aggregation of platelets in vitro were carried out,Together with the blood vicosity, plasma viscosity,the aggregation of red blood cell the rigidity of red blood cell and fibrinogen were de- termined.Results:The outcome showed the high predisposition to sludging,statises and thrombophilia; and the increase of the adhensive aggregation of platelets (P<0.001)and the increase of fibrinogen raised the vicosity of blood.This may be helpful to the clinical therapy of cancer.
出处
《介入放射学杂志》
CSCD
1998年第1期22-24,共3页
Journal of Interventional Radiology
