摘要
药物及化学中毒主要通过损伤或抑制造血干祖细胞,导致造血功能衰竭,使红细胞生成减少或影响红细胞寿命而引发贫血。详细病史询问和体格检查能提供许多线索,实验室检查有助于进一步明确贫血类型。应及时脱离致病药物及化学物的接触,排出和中和毒性物质,积极支持治疗和对症治疗。部分患者应长期随访,评价病情变化。
Drugs or toxic chemicals related anemia was mainly mediated by suppression of hematopoietical stem cells and/or precursors, then caused hematopoietical failure;or shortened the survival of red cells. Carefully gathering information of history and physical examination was vital,and experiment examinations could also make definitely classifications of anemia. Detachment, excretion and neutralization of these drugs or toxic chemicals should be conducted in time, support care and anti symptomatic therapy would be very useful. Long-term followingup for some patients was necessary to evaluate the transformation of disease.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2009年第7期599-602,共4页
Chinese Journal of Practical Internal Medicine
关键词
贫血
化学性药物
anemia
toxic chemical drugs
