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血管化组织工程骨构建的研究进展

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摘要 1血管化在组织工程骨构建中的作用 新生血管不仅是参与修复的细胞信号分子通过的重要途径,也是氧气、各种营养成分及代谢废物的运输通道,从整体上维持骨修复的代谢微环境。以生长因子、种子细胞、载体支架为基础的骨组织工程研究取得了很大成功,向人们展示了再造骨组织器官的美好前景,然而在临床应用方面尚少有尝试。究其原因,组织工程骨很大程度上受制于移植物血管网缺乏造成的细胞供养障碍而导致失效。
出处 《中国医药导刊》 2009年第5期718-720,共3页 Chinese Journal of Medicinal Guide
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