摘要
目的研究降脂消斑片对高脂血症脂质代谢的影响。方法高脂饲料喂养4个月加免疫损伤制备家兔高脂血症合并动脉粥样硬化模型。用降脂消斑方口服给药治疗8周,检测血TC、TG、LDC-C、HDL-C、ApoA、ApoB,并计算动脉硬化指数(AI)。结果与模型组比较,降脂消斑方明显降低血清TC、TG、LDL-C、Apo-B及AI,差异均具有统计学意义(P<0.05)。结论降脂消斑片有降低血脂的作用,能改善高脂血症的血脂代谢,降低动脉粥样硬化风险指数。
Objective To study the effects of Jiangzhi Xiaoban tablet on lipid metabolism. Methods The high fat diet with immunologic injury was continued to feed the models with atherosclerosis and hypedipidemia. After treating with the tablet 8 weeks, the blood lipid levels,such as serum TC, TG, LDC-C, HDL-C, ApoA, ApoB and AI were determined. Results Compared with the model group, the tablet could decrease the level of serum TC, TG, LDL-C, and Apo-B, the difference of AI was remarkable（P〈0.05）. Conclusion Jiangzhi Xiaoban tablet is effective to decrease the blood lipid, improve lipid metabolism and reduce hyperlipidemia AI.
出处
《湖南中医药大学学报》
CAS
2009年第3期21-23,共3页
Journal of Hunan University of Chinese Medicine
基金
湖南省教育厅科研基金资助项目(05C360)
关键词
动脉粥样硬化
高脂血症
脂质代谢
降脂消斑片
兔
虎杖
黄芪
大黄
atherosclerosis
hyperlipidemia
lipid metabolism
Jiangzhi Xiaoban tablet
rabbits
polygonum cuspindatum
astraglus base
Chinese rhubarb
